A pilot study examining functional brain activity 6 months after memory retraining in MS: the MEMREHAB trial.
A pilot study examining functional brain activity 6 months after memory retraining in MS: the MEMREHAB trial.
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DOI：
10.1007/s11682-014-9309-9
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发表时间：
2014-09
影响因子：
3.2
通讯作者：
Chiaravalloti, Nancy D.
中科院分区：
文献类型：
--
作者：
Dobryakova, Ekaterina;Wylie, Glenn R.;DeLuca, John;Chiaravalloti, Nancy D.
多发性硬化症 (MS) 患者的认知障碍现已得到广泛认可。最常见的认知缺陷之一是记忆功能，这主要是由于习得能力受损。检查多发性硬化症患者记忆再训练后 6 个月的大脑功能活动。本报告介绍了一项记忆康复方案（称为改良故事记忆技术）的随机临床试验的长期随访结果。所有参与者的行为记忆表现和大脑活动均在基线、治疗后立即和治疗后 6 个月进行评估。结果显示，之前观察到的记忆训练后学习过程中大脑激活模式的增加在训练后 6 个月仍保持不变。
Cognitive impairment in individuals with multiple sclerosis (MS) is now well recognized. One of the most common cognitive deficits is found in memory functioning, largely due to impaired acquisition. Examine functional brain activity 6 months after memory retraining in individuals with MS. The current report presents long term follow-up results from a randomized clinical trial on a memory rehabilitation protocol known as the modified Story Memory Technique. Behavioral memory performance and brain activity of all participants were evaluated at baseline, immediately after treatment, and 6 months after treatment. Results revealed that previously observed increases in patterns of cerebral activation during learning immediately after memory training were maintained 6 months post training.
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影响因子：
11.2
作者：
McDonald, WI;Compston, A;Wolinsky, JS
通讯作者：
Wolinsky, JS
影响因子：
9.9
作者：
Chiaravalloti, Nancy D.;Moore, Nancy B.;DeLuca, John
通讯作者：
DeLuca, John
影响因子：
5.8
作者：
Parisi, Laura;Rocca, Maria A.;Filippi, Massimo
通讯作者：
Filippi, Massimo
影响因子：
3.9
作者：
Chiaravalloti, Nancy D.;Balzano, Julie;DeLuca, John
通讯作者：
DeLuca, John
影响因子：
4.2
作者：
Cerasa, Antonio;Gioia, Maria Cecilia;Quattrone, Aldo
通讯作者：
Quattrone, Aldo