Applying what we know to accelerate cancer prevention.
Applying what we know to accelerate cancer prevention.
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DOI：
10.1126/scitranslmed.3003218
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发表时间：
2012-03-28
影响因子：
17.1
通讯作者：
Gehlert S
中科院分区：
文献类型：
--
作者：
Colditz GA;Wolin KY;Gehlert S
今天发生的癌症中有一半以上是可以通过应用我们已经掌握的知识来预防的。烟草、肥胖和缺乏体育锻炼是可改变的癌症病因，它们产生的疾病最多。癌症负担可以通过改变个人和群体行为以及公共卫生努力来减少，只要这些变化是由健全的科学知识和社会承诺来推动的。这些努力的障碍是社会性的，来自包括学术界在内的机构的组织以及日常生活的习惯。为了实现最大可能的癌症预防，我们将需要更好的方法来实施我们所知道的，并改善基础设施，以更好地激励和支持跨学科，多层次的研究和成功的干预。
More than half of the cancer occurring today is preventable by applying knowledge that we already have. Tobacco, obesity, and physical inactivity are the modifiable causes of cancer that generate the most disease. Cancer burden can be reduced by alterations in individual and population behaviors and by public health efforts as long as these changes are driven by sound scientific knowledge and social commitment to change. The obstacles to these efforts are societal and arise from the organization of institutions, including academia, and in the habits of daily life. To achieve maximal possible cancer prevention, we will need better ways to implement what we know and improved infrastructure that will better incentivize and support transdisciplinary, multilevel research and successful intervention.
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影响因子：
168.9
作者：
Burn, John;Gerdes, Anne-Marie;Macrae, Finlay;Mecklin, Jukka-Pekka;Moeslein, Gabriela;Olschwang, Sylviane;Eccles, Diane;Evans, D. Gareth;Maher, Eamonn R.;Bertario, Lucio;Bisgaard, Marie-Luise;Dunlop, Malcolm G.;Ho, Judy W. C.;Hodgson, Shirley V.;Lindblom, Annika;Lubinski, Jan;Morrison, Patrick J.;Murday, Victoria;Ramesar, Raj;Side, Lucy;Scott, Rodney J.;Thomas, Huw J. W.;Vasen, Hans F.;Barker, Gail;Crawford, Gillian;Elliott, Faye;Movahedi, Mohammad;Pylvanainen, Kirsi;Wijnen, Juul T.;Fodde, Riccardo;Lynch, Henry T.;Mathers, John C.;Bishop, D. Timothy
通讯作者：
Bishop, D. Timothy
DOI：
10.1158/1055-9965.epi-11-0628
发表时间：
2011-09
期刊：
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
影响因子：
--
作者：
Gehlert S;Colditz GA
通讯作者：
Colditz GA
影响因子：
39.2
作者：
Angell, Sonia Y.;Silver, Lynn Dee;Bassett, Mary T.
通讯作者：
Bassett, Mary T.
影响因子：
168.9
作者：
Danaei, G;Vander Hoorn, S;Ezzati, M
通讯作者：
Ezzati, M
影响因子：
8
作者：
Berkey CS;Willett WC;Frazier AL;Rosner B;Tamimi RM;Rockett HR;Colditz GA
通讯作者：
Colditz GA