Diet Quality and Long-Term Absolute Risks for Incident Cardiovascular Disease and Mortality.
Diet Quality and Long-Term Absolute Risks for Incident Cardiovascular Disease and Mortality.
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DOI：
10.1016/j.amjmed.2020.08.012
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发表时间：
2021-04
期刊：
影响因子：
--
通讯作者：
Allen NB
中科院分区：
文献类型：
--
作者：
Zhong VW;Ning H;Van Horn L;Carnethon MR;Wilkins JT;Lloyd-Jones DM;Allen NB
根据不同成人年龄的饮食质量，心血管疾病和死亡率的长期绝对风险以及无心血管疾病生存率尚不清楚。分析了1985-2016年收集的6个前瞻性队列的数据（n= 29，497）。通过替代健康饮食指数2010（aHEI-2010）、替代地中海（aMED）饮食评分和停止高血压饮食方法（DASH）评分评估基线饮食质量。采用改良Kaplan-Meier分析法估计绝对风险，采用欧文限制平均值估计无心血管疾病生存率。分析按性别和基线年龄分层：年轻（20-39岁）、中年（40-59岁）和老年（60-79岁）。比较aHEI-2010评分最低五分位和最高五分位的参与者，40年心血管疾病事件的风险为14.3%。（95%可信区间：10.0-18.6）vs 5.9%（3.0-8.9）青年男子，8.8%（4.3-13.3）vs 3.0%青年女性为39.6%（36.1-43.2）vs 30.8%（26.2-35.3），中年女性为32.9%（28.0-37.8）vs 19.5%（16.6-22.4）。对于老年人，30年内发生心血管疾病的风险为54.7%（49.3-60.2），男性为49.7%（44.5-55.0），女性为48.3%（44.0-52.5）和42.4%（38.2-46.7）。全因死亡率也有类似的负相关。与aHEI-2010评分最低的五分之一的参与者相比，最高五分之一的参与者的无心血管疾病生存期延长了约0.5-2.2年。基于DASH评分而非aMED评分的结果与基于aHEI-2010评分的结果相似。无论饮食评估时的性别或年龄如何，食用更高质量的饮食与心血管疾病和死亡率的长期绝对风险降低以及无心血管疾病生存期延长相关。
Long-term absolute risks for cardiovascular disease and mortality and cardiovascular disease-free survival according to diet quality at different adult ages are unclear. Data from 6 prospective cohorts collected in 1985–2016 were analyzed (n=29,497). Baseline diet quality was assessed by alternate Healthy Eating Index 2010 (aHEI-2010), alternate Mediterranean (aMED) diet score, and Dietary Approaches to Stop Hypertension (DASH) score. Absolute risks were estimated using modified Kaplan-Meier analysis and cardiovascular disease-free survival using Irwin’s restricted mean. Analyses were stratified by sex and baseline age: young (20–39 years), middle-aged (40–59), and older (60–79). Comparing participants in the lowest quintile with those in the highest quintile of aHEI-2010 score, the 40-year risks for incident cardiovascular disease were 14.3% (95% CI: 10.0–18.6) vs 5.9% (3.0–8.9) in young men, 8.8% (4.3–13.3) vs 3.0% (1.6–4.4) in young women, 39.6% (36.1–43.2) vs 30.8% (26.2–35.3) in middle-aged men, and 32.9% (28.0–37.8) vs 19.5% (16.6–22.4) in middle-aged women. For older adults, the 30-year risks for incident cardiovascular disease were 54.7% (49.3–60.2) vs 49.7% (44.5–55.0) in men and 48.3% (44.0–52.5) vs 42.4% (38.2–46.7) in women. Similar inverse associations were identified for all-cause mortality. Compared with participants in the lowest quintile of aHEI-2010 score, those in the highest quintile had ~0.5–2.2 years of longer cardiovascular disease-free survival. Results based on DASH score, but not aMED score, were similar to results based on aHEI-2010 score. Consuming a higher quality diet was associated with lower long-term absolute risks for cardiovascular disease and mortality and longer cardiovascular disease-free survival, regardless of sex or age at dietary assessment.
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影响因子：
37.8
作者：
Huffman MD;Capewell S;Ning H;Shay CM;Ford ES;Lloyd-Jones DM
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10.1016/j.jand.2012.08.011
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