Evaluating two respiratory correction methods for abdominal PET/MRI imaging.
Evaluating two respiratory correction methods for abdominal PET/MRI imaging.
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评估腹部 PET/MRI 成像的两种呼吸校正方法
DOI：
10.1186/s40658-022-00430-w
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发表时间：
2022-01-31
期刊：
影响因子：
4
通讯作者：
Lan X
中科院分区：
文献类型：
--
作者：
Ruan W;Liu F;Sun X;Hu F;Wu T;Zhang Y;Lan X
为评价两种腹部PET/MRI图像的呼吸校正方法，并进一步分析其对呼吸运动校正标准摄取值(SUV)的影响，对17例患者的25个腹部18F-FDG PET/CT病灶进行了PET/MRI扫描。采用呼气末呼吸门控和多仓呼吸门控重建PET图像。同时，对完整数据和S无呼吸门控前3分钟和20分钟的数据进行重建以进行评价。计算病灶的最大血流速度和平均血流速度，背景的平均血流速度和标准差，以及信噪比等5个参数，并进行统计学比较。计算多仓呼吸门控和全数据重建相对于S获得的前3分钟和20分钟数据重建的差异。与PET/CT相比，腹部PET/MRI扫描时间较长，需要对呼吸运动进行校正。多通道呼吸门控矫正术能明显降低图像模糊，提高病灶的最大血流速度(11.98%)和平均血流速度(13.12%)(p<0.05)，对腹部 = 图像的显示效果明显优于呼气末呼吸门控。呼吸运动校正引起的最大呼气量增加值与校正后计数丢失引起的增加值无显著差异(p = 0.39)，而以往的研究报道较少。根据目前的参数，多仓呼吸门控方法比末端呼吸门控方法更能有效地纠正腹部PET/MRI中的呼吸运动。然而，由于PET数据被丢弃的事实，门控图像中的噪声增加是SUVmax增加的部分原因。
To evaluate two respiratory correction methods for abdominal PET/MRI images and further to analyse the effects on standard uptake values (SUVs) of respiratory motion correction, 17 patients with 25 abdominal lesions on 18F-FDG PET/CT were scanned with PET/MRI. PET images were reconstructed using end-expiratory respiratory gating and multi-bin respiratory gating. Meanwhile, full data and the first 3 min and 20 s of data acquired both without respiratory gating were reconstructed for evaluation. Five parameters, including the SUVmax and SUVmean in the lesions, the SUVmean and standard deviation (SD) in the background, and the signal-to-noise ratio (SNR), were calculated and used for statistical comparisons. The differences in multi-bin respiratory gating and reconstruction of full data, relative to the reconstruction of the first 3 min and 20 s of data acquired, were calculated. Compared with PET/CT, the longer scanning time of abdominal PET/MRI makes respiratory motion correction necessary. The multi-bin respiratory gating correction could reduce the PET image blur and increase the SUVmax (11.98%) and SUVmean (13.12%) of the lesions significantly (p = 0.00), which was much more effective than end-expiratory respiratory gating for abdominal PET/MRI. The added value of SUVmax caused by respiratory motion correction has no significant difference compared with that caused by count loss with the correction (p = 0.39), which was rarely reported by previous studies. Based on the current parameters, the method of multi-bin respiratory gating was more effective for respiratory motion correction in abdominal PET/MRI in comparisons with the method of end-respiratory gating. However, the increased noise in gated images, due to the fact that PET data get discarded, is partly responsible for the increase in SUVmax.
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影响因子：
3.8
作者：
Dawood, Mohammad;Buether, Florian;Schaefers, Klaus P.
通讯作者：
Schaefers, Klaus P.
影响因子：
5.9
作者：
Grootjans, Willem;de Geus-Oei, Lioe-Fee;Visser, Eric P.
通讯作者：
Visser, Eric P.
DOI：
10.1002/anie.201805501
发表时间：
2019-02-25
期刊：
Angewandte Chemie (International ed. in English)
影响因子：
--
作者：
Deng X;Rong J;Wang L;Vasdev N;Zhang L;Josephson L;Liang SH
通讯作者：
Liang SH
影响因子：
9.3
作者：
Soret, Marine;Bacharach, Stephen L.;Buvat, Irene
通讯作者：
Buvat, Irene
影响因子：
1.3
作者：
van der Vos, Charlotte S.;Grootjans, Willem;Visser, Eric P.
通讯作者：
Visser, Eric P.