Precision and agreement of higher order aberrations measured with ray tracing and Hartmann-Shack aberrometers.
Precision and agreement of higher order aberrations measured with ray tracing and Hartmann-Shack aberrometers.
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用射线示踪和Hartmann-Shack类差异测量的高阶畸变的精度和一致性。
DOI：
10.1186/s12886-018-0683-8
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发表时间：
2018-01-27
影响因子：
2
通讯作者：
Wu Q
中科院分区：
文献类型：
--
作者：
Xu Z;Hua Y;Qiu W;Li G;Wu Q
旨在评估使用光线跟踪像差仪（iTrace）和Hartmann-Shack像差仪（Topcon KR-1 W）获得的高阶像差（HOA）测量的精度和一致性。诊断试验的前瞻性评价。本研究包括使用这两种装置获得的92名正常受试者右眼的数据。两名观察员进行3次连续扫描，以确定观察员内重复性和观察员间重复性。大约一周后，一名观察员进行另外3次连续扫描，以获得会话间再现性。采用受试者内标准差（Sw）、重复性（TRT）和组内相关系数（ICC）评价精密度，采用Bland-Altman图评价一致性。对于眼部、角膜和内部HOA的观察者内重复性，Topcon KR-1 W显示2.77 Sw ≤ 0.079 μm，ICC ≥ 0.761; iTrace显示2.77 Sw ≤ 0.105 μm，ICC ≥ 0.805。除球面像差（SA）（0.862）外，观察者间重现性的内部HOA的ICC均小于0.75，而对应的观察者间重现性显示出相似但较低的结果。Topcon KR-1 W和iTrace之间的眼部、角膜和内部HOA测量值存在统计学显著性差异（均P < 0.05）。在眼SA和内部昏迷方面没有观察到显著差异。光线追迹法和哈特曼-夏克法像差仪在高阶像差测量中具有良好的重复性，但可靠性较差（SA除外）。由于两种像差仪测量的高阶像差存在显著差异，在临床应用中不能互换。
To assess the precision and agreement of measurements of higher order aberrations (HOAs) obtained with a ray tracing aberrometer (iTrace) and a Hartmann-Shack aberrometer (Topcon KR-1 W). Prospective evaluation of the diagnostic test. Data from the right eyes of 92 normal subjects obtained using the two devices were included in this study. Two observers performed 3 consecutive scans to determine the intraobserver repeatability and interobserver reproducibility. About one week later, one observer performed an additional 3 consecutive scans to obtain the intersession reproducibility. The within-subject standard deviation (Sw), test-retest repeatability (TRT) and intraclass correlation coefficient (ICC) were used to assess the precision, while Bland-Altman plots were performed to assess the agreement. For intraobserver repeatability of the ocular, corneal and internal HOAs, Topcon KR-1 W showed a 2.77Sw of 0.079 μm or less and ICCs of 0.761 or more; and iTrace showed a 2.77Sw of 0.105 μm or less and ICCs of 0.805 or more. The ICCs of the internal HOAs of interobserver reproducibility were less than 0.75 except for spherical aberration (SA) (0.862), and interobserver reproducibility of the counterpart showed similar but lower results. For the ocular, corneal and internal HOA measurements, statistically significant differences existed between the Topcon KR-1 W and iTrace (all P < 0.05). No significant differences were observed in the ocular SA and internal coma. The ray tracing and Hartmann-Shack method aberrometers provided excellent repeatability but less reliable reproducibility in the measurement of HOAs (except for SA). The two aberrometers should not be interchangeable in clinical application because of the significant differences in HOA measurements between them.
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