The insula of Reil revisited: multiarchitectonic organization in macaque monkeys.
The insula of Reil revisited: multiarchitectonic organization in macaque monkeys.
复制标题
DOI：
10.1093/cercor/bhr104
复制
发表时间：
2012-01
期刊：
影响因子：
--
通讯作者：
Morel A
中科院分区：
文献类型：
--
作者：
Gallay DS;Gallay MN;Jeanmonod D;Rouiller EM;Morel A
雷尔氏沟代表了一个大的皮层区域，埋在外侧沟的深处，并细分为3个主要的细胞结构域：无颗粒，dysgranular和颗粒。本研究的目的是重新调查的建筑组织的猴子的神经纤维使用多种免疫组织化学染色（小清蛋白，PV，非磷酸化神经丝蛋白，SMI-32，乙酰胆碱酯酶，AChE）除了尼氏和髓鞘。根据神经化学标记物的密度和层状分布的变化，划分了几个区域，并将其与8个细胞结构亚群（Ia 1-Ia 2/Id 1-Id 3/Ig 1-Ig 2/G）相关联。比较未折叠的海马地图上的不同染色模式，发现：（1）中间层髓鞘、PV和AChE阳性纤维和颗粒上层SMI-32锥体神经元呈腹侧向背侧平行梯度增加，后髓背侧和腹侧高密度带合并; 2）“适当”脑岛的定义仅限于“形态”脑岛的三分之二（以限制沟为界），最明显的特征是PV较低，3）腹侧缘沿着其背侧，背后，和后腹侧边缘由一条皮质延伸超出形态学的边界，并与额顶叶和颞盖区相关的味觉，躯体感觉和听觉方式连续的架构。
The insula of Reil represents a large cortical territory buried in the depth of the lateral sulcus and subdivided into 3 major cytoarchitectonic domains: agranular, dysgranular, and granular. The present study aimed at reinvestigating the architectonic organization of the monkey's insula using multiple immunohistochemical stainings (parvalbumin, PV; nonphosphorylated neurofilament protein, with SMI-32; acetylcholinesterase, AChE) in addition to Nissl and myelin. According to changes in density and laminar distributions of the neurochemical markers, several zones were defined and related to 8 cytoarchitectonic subdivisions (Ia1–Ia2/Id1–Id3/Ig1–Ig2/G). Comparison of the different patterns of staining on unfolded maps of the insula revealed: 1) parallel ventral to dorsal gradients of increasing myelin, PV- and AChE-containing fibers in middle layers, and of SMI-32 pyramidal neurons in supragranular layers, with merging of dorsal and ventral high-density bands in posterior insula, 2) definition of an insula “proper” restricted to two-thirds of the “morphological” insula (as bounded by the limiting sulcus) and characterized most notably by lower PV, and 3) the insula proper is bordered along its dorsal, posterodorsal, and posteroventral margin by a strip of cortex extending beyond the limits of the morphological insula and continuous architectonically with frontoparietal and temporal opercular areas related to gustatory, somatosensory, and auditory modalities.
登录
查看更多内容
影响因子：
2.5
作者：
BURTON, H;FABRI, M;ALLOWAY, K
通讯作者：
ALLOWAY, K
影响因子：
2.5
作者：
Coq, JO;Qi, H;Kaas, JH
通讯作者：
Kaas, JH
影响因子：
2.5
作者：
FRIEDMAN, DP;MURRAY, EA
通讯作者：
MURRAY, EA
影响因子：
4.9
作者：
de Araujo, I. E.;Simon, S. A.
通讯作者：
Simon, S. A.
影响因子：
2.5
作者：
HOF, PR;NIMCHINSKY, EA;MORRISON, JH
通讯作者：
MORRISON, JH