Time-Resolved Diffuse Optical Spectroscopy and Imaging Using Solid-State Detectors: Characteristics, Present Status, and Research Challenges
Time-Resolved Diffuse Optical Spectroscopy and Imaging Using Solid-State Detectors: Characteristics, Present Status, and Research Challenges
复制标题
使用固态探测器的时间分辨漫反射光谱和成像：特征、现状和研究挑战
DOI：
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
M. Deen
中科院分区：
文献类型：
--
作者：
M. Alayed;M. Deen
扩散光学光谱（DOS）和扩散光学成像（DOI）是新兴的非侵入性成像模式，在许多领域具有广泛的潜在应用，特别是在医学中的结构和功能成像。在这篇文章中，我们回顾了时间分辨扩散光学成像（TR-DOI）系统使用固态探测器，特别关注单光子雪崩二极管（SPAD）和硅光电倍增管（SiPM）。这些TR-DOI系统可以根据探测器的操作模式（自由运行或时间选通）分为两种类型。对于TR-DOI原型，描述了物理概念、主要部件、探测器的品质因数和评估参数。TR-DOI原型的性能是根据通用协议中使用的参数进行评估的，以测试DOI系统，特别是基本仪器性能（BIP）。此外，SPAD和SiPM的潜在功能，以改善TR-DOI系统和扩大其应用在可预见的未来进行了讨论。最后，研究的挑战和未来的发展TR-DOI讨论了原型中的每个组件单独和整个系统。
Diffuse optical spectroscopy (DOS) and diffuse optical imaging (DOI) are emerging non-invasive imaging modalities that have wide spread potential applications in many fields, particularly for structural and functional imaging in medicine. In this article, we review time-resolved diffuse optical imaging (TR-DOI) systems using solid-state detectors with a special focus on Single-Photon Avalanche Diodes (SPADs) and Silicon Photomultipliers (SiPMs). These TR-DOI systems can be categorized into two types based on the operation mode of the detector (free-running or time-gated). For the TR-DOI prototypes, the physical concepts, main components, figures-of-merit of detectors, and evaluation parameters are described. The performance of TR-DOI prototypes is evaluated according to the parameters used in common protocols to test DOI systems particularly basic instrumental performance (BIP). In addition, the potential features of SPADs and SiPMs to improve TR-DOI systems and expand their applications in the foreseeable future are discussed. Lastly, research challenges and future developments for TR-DOI are discussed for each component in the prototype separately and also for the entire system.
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影响因子：
2.9
作者：
CHANCE, B;NIOKA, S;HOLTOM, G
通讯作者：
HOLTOM, G
DOI：
10.1063/1.4875593
发表时间：
2014-05
期刊：
The Review of scientific instruments
影响因子：
--
作者：
R. Cooper;Elliott Magee;N. Everdell;S. Magazov;M. Varela;D. Airantzis;A. Gibson;J. Hebden
通讯作者：
R. Cooper;Elliott Magee;N. Everdell;S. Magazov;M. Varela;D. Airantzis;A. Gibson;J. Hebden
影响因子：
1.9
作者：
Dehghani, H;Pogue, BW;Paulsen, KD
通讯作者：
Paulsen, KD
影响因子：
3.4
作者：
Goff DA;Buckley EM;Durduran T;Wang J;Licht DJ
通讯作者：
Licht DJ