The influence of early exposure to tobacco smoke for pulmonary disease
The influence of early exposure to tobacco smoke for pulmonary disease
复制标题
早期接触烟草烟雾对肺部疾病的影响
DOI：
10.7143/jhep.39.540
复制
发表时间：
2011
影响因子：
24.3
通讯作者：
I. Kuwahira
中科院分区：
文献类型：
--
作者：
A. Ebihara;A. Nagai;Takayuki Nakano;T. Iwamoto;I. Kuwahira
背景：吸烟是慢性阻塞性肺疾病、肺癌等慢性肺部疾病的一个非常严重的问题。然而，关于早期接触烟草烟雾的研究很少。日本的吸烟率降至21.8%。然而，北部地区(北海道)的失业率仍然较高。特别是在Erimo镇(北海道最南端)，这一比例为31.0%，高于北海道的任何其他城市。原因是父母吸烟时，孩子放火焚烧烟草，并在20世纪40年代将其作为一种习俗递给了孩子。由于钓鱼时一只手湿了，他们自己无法放火。目的：评价早期接触烟草烟雾对慢性阻塞性肺疾病和肺癌患病率的影响。方法：利用埃里莫镇卫生局和镇卫生室的体检结果，对约6000名居民的流行病学资料进行分析。结果：大多数居民从小就主动或被动地接触到烟草烟雾。室友吸烟率为81.0%。慢性呼吸系统疾病死亡率为71.4/10万人年，远远超过全国平均水平(11.4/10万人年)。慢性阻塞性肺病患病率(每100,000人年465.5人)显著高于全国平均水平(每100,000人年136.2人)。肺癌患病率也很高(每100,000人年877.2人)。结论：儿童早期暴露于烟草烟雾显著增加了COPD和肺癌的患病率。在日本，年轻一代的吸烟率仍然很高(209岁的人占14.3%，309岁的人占18.0%)。戒烟是防止疾病进展的最重要的干预措施。
Background: Smoking is a very serious problem for COPD, lung cancer and other chronic pulmonary diseases. However, there are few studies on early exposure to tobacco smoke. Smoking rate in Japan decreased to 21.8%. However it is still higher in the northern area (Hokkaido). In particularly, it is 31.0% in Erimo town (southernmost extreme of Hokkaido), which is higher than that of any other cities in Hokkaido. The reason is that when parents smoked, the child set fire to tobacco and handed it as a custom in 19409s. Because a hand was wet while fishing, they were not able to set fire themselves. Aim: We evaluated the influence of early exposure to tobacco smoke on prevalence of COPD and lung cancer. Methods: Using the results of the medical checkup carried out at the Erimo town health division and the Town clinic, we analyzed about 6000 residents9 epidemiologic data. Results: Majority of residents were found exposed to tobacco smoke actively or passively from a young age. Housemate smoking rate was 81.0%. The mortality of chronic respiratory disease was 71.4 per 100,000 person-years that was far exceeded from the national average (11.4 per 100,000 person-years). COPD prevalence (465.5 per 100,000 person-years) was significantly higher than the national average (136.2 per 100,000 person-years). Lung cancer prevalence was also very high (877.2 per 100,000 person-years). Conclusion: Early exposure to tobacco smoke in childhood significantly increases prevalence of COPD and lung cancer. In Japan, young generation showed still high smoking rates (14.3% aged 209s, 18.0% aged 309s). Smoking cessation is the most important intervention to prevent disease progression.
环境香烟烟雾暴露调节了PB暴露儿童的IgE水平。
影响因子：
4.5
作者：
Lutz PM;Kelty EA;Brown TD;Wilson TJ;Brock G;Neal RE
通讯作者：
Neal RE
影响因子：
10
作者：
Sørheim IC;Johannessen A;Gulsvik A;Bakke PS;Silverman EK;DeMeo DL
通讯作者：
DeMeo DL