Prostate cancer chemoprevention by natural agents: Clinical evidence and potential implications.
Prostate cancer chemoprevention by natural agents: Clinical evidence and potential implications.
复制标题
天然药物化学预防前列腺癌：临床证据和潜在影响。
DOI：
10.1016/j.canlet.2018.02.025
复制
发表时间：
2018-05-28
期刊：
影响因子：
9.7
通讯作者：
Ahmad N
中科院分区：
文献类型：
--
作者：
Chhabra G;Singh CK;Ndiaye MA;Fedorowicz S;Molot A;Ahmad N
Prostate cancer (PCa) is the most common non-skin cancer and the second leading cause of cancer-related deaths in American men. Due to its long latency period, PCa is considered as an ideal cancer type for chemopreventive interventions. Chemopreventive agents include various natural or synthetic agents that prevent or delay cancer development, progression and/or recurrence. Pre-clinical studies suggest that many natural products and dietary agents have chemopreventive properties. However, a limited number of these agents have been tested in clinical trials, with varying success. In this review, we have discussed the available clinical studies regarding the efficacy of natural chemopreventive agents against PCa, including tea polyphenols, selenium, soy proteins, vitamins and resveratrol. We have also provided a discussion on the clinical challenges and opportunities for the potential use of chemopreventive agents against PCa. Based on available literature, it appears that the variable outcomes of the chemopreventive clinical studies necessitate a need for additional studies with more rigorous designs and methodical interpretations in order to measure the potential of the natural agents against PCa.
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影响因子：
168.9
作者：
Grönberg, H
通讯作者：
Grönberg, H
影响因子：
3.7
作者：
Hamilton-Reeves JM;Banerjee S;Banerjee SK;Holzbeierlein JM;Thrasher JB;Kambhampati S;Keighley J;Van Veldhuizen P
通讯作者：
Van Veldhuizen P
影响因子：
4.2
作者：
Henning, Susanne M.;Aronson, William;Heber, David
通讯作者：
Heber, David
影响因子：
10.3
作者：
Geybels, Milan S.;Verhage, Bas A. J.;van den Brandt, Piet A.
通讯作者：
van den Brandt, Piet A.
DOI：
10.1093/jnci/djw153
发表时间：
2016-11
期刊：
Journal of the National Cancer Institute
影响因子：
--
作者：
Allen NE;Travis RC;Appleby PN;Albanes D;Barnett MJ;Black A;Bueno-de-Mesquita HB;Deschasaux M;Galan P;Goodman GE;Goodman PJ;Gunter MJ;Heliövaara M;Helzlsouer KJ;Henderson BE;Hercberg S;Knekt P;Kolonel LN;Lasheras C;Linseisen J;Metter EJ;Neuhouser ML;Olsen A;Pala V;Platz EA;Rissanen H;Reid ME;Schenk JM;Stampfer MJ;Stattin P;Tangen CM;Touvier M;Trichopoulou A;van den Brandt PA;Key TJ;Endogenous Hormones, Nutritional Biomarkers and Prostate Cancer Collaborative Group
通讯作者：
Endogenous Hormones, Nutritional Biomarkers and Prostate Cancer Collaborative Group