The PTI to ETI Continuum in Phytophthora-Plant Interactions.
The PTI to ETI Continuum in Phytophthora-Plant Interactions.
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Phytophthora-植物相互作用中的PTI到ETI连续体。
DOI：
10.3389/fpls.2020.593905
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发表时间：
2020
影响因子：
5.6
通讯作者：
Ali GS
中科院分区：
文献类型：
--
作者：
Naveed ZA;Wei X;Chen J;Mubeen H;Ali GS
疫霉是几种重要经济作物的臭名昭著的病原菌。来自疫霉菌的几种一般启动子，通常被称为病原体相关分子模式（Pathogen-Associated Molecular Patterns, PAMPs），已经被植物受体识别，并在被称为pamp触发免疫（PTI）的过程中触发诱导防御反应。适应性疫霉病原体进化出多种策略来逃避PTI。它们可以修饰或抑制其激发子以避免被宿主识别，并通过部署数百种效应物来调节宿主防御反应，这些效应物通过调节涉及钙和MAPK信号传导、选择性剪接、RNA干扰、囊泡运输、细胞间运输、蛋白质水解和植物激素信号通路的成分来抑制宿主防御和生理过程。在不相容的相互作用中，抗性寄主植物通过抗性蛋白感知效应诱导的调节，并以一种更快、更强大的方式激活下游防御反应的成分，这种方式被称为效应触发免疫（ETI）。当病原体克服pti时——通常是在没有R蛋白的情况下通过效应物——效应物引发的易感性（ETS）随之而来。从质量上讲，许多下游防御反应在PTI和ETI之间重叠。总的来说，植物与植物相互作用的多个阶段遵循PTI-ETS-ETI模式，该模式最初是在植物免疫的之字形模型中提出的。然而，基于几个例子，在植物-植物相互作用中，这些阶段之间的界限并不明显，而是混合的，指向一个PTI-ETI连续体。
Phytophthora species are notorious pathogens of several economically important crop plants. Several general elicitors, commonly referred to as Pathogen-Associated Molecular Patterns (PAMPs), from Phytophthora spp. have been identified that are recognized by the plant receptors to trigger induced defense responses in a process termed PAMP-triggered Immunity (PTI). Adapted Phytophthora pathogens have evolved multiple strategies to evade PTI. They can either modify or suppress their elicitors to avoid recognition by host and modulate host defense responses by deploying hundreds of effectors, which suppress host defense and physiological processes by modulating components involved in calcium and MAPK signaling, alternative splicing, RNA interference, vesicle trafficking, cell-to-cell trafficking, proteolysis and phytohormone signaling pathways. In incompatible interactions, resistant host plants perceive effector-induced modulations through resistance proteins and activate downstream components of defense responses in a quicker and more robust manner called effector-triggered-immunity (ETI). When pathogens overcome PTI—usually through effectors in the absence of R proteins—effectors-triggered susceptibility (ETS) ensues. Qualitatively, many of the downstream defense responses overlap between PTI and ETI. In general, these multiple phases of Phytophthora-plant interactions follow the PTI-ETS-ETI paradigm, initially proposed in the zigzag model of plant immunity. However, based on several examples, in Phytophthora-plant interactions, boundaries between these phases are not distinct but are rather blended pointing to a PTI-ETI continuum.
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影响因子：
4.4
作者：
Attard, Agnes;Evangelisti, Edouard;Gourgues, Mathieu
通讯作者：
Gourgues, Mathieu
影响因子：
16.6
作者：
Boevink PC;Wang X;McLellan H;He Q;Naqvi S;Armstrong MR;Zhang W;Hein I;Gilroy EM;Tian Z;Birch PRJ
通讯作者：
Birch PRJ
DOI：
10.1071/fp09304
发表时间：
2010-05-20
期刊：
Functional plant biology : FPB
影响因子：
--
作者：
Anderson JP;Gleason CA;Foley RC;Thrall PH;Burdon JB;Singh KB
通讯作者：
Singh KB
影响因子：
56.9
作者：
Austin, MJ;Muskett, P;Parker, JE
通讯作者：
Parker, JE
影响因子：
11.4
作者：
Brunner, F;Rosahl, S;Nürnberger, T
通讯作者：
Nürnberger, T