Developing Empirical Latent Profiles of Impulsive Aggression and Mood in Youths across Three Outpatient Samples.
Developing Empirical Latent Profiles of Impulsive Aggression and Mood in Youths across Three Outpatient Samples.
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DOI：
10.1080/15374416.2021.1929251
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发表时间：
2023-03
影响因子：
4.2
通讯作者：
Findling, Robert L.
中科院分区：
文献类型：
--
作者：
Youngstrom, Eric A.;Young, Andrea S.;Van Eck, Katherine;Stepanova, Ekaterina;Langfus, Joshua A.;Carlson, Gabrielle;Findling, Robert L.
冲动性和反应性攻击（AIR）可以将一部分青少年与那些有注意力问题、违规行为或情绪障碍的青少年区分开来，可能具有不同的治疗反应。然而，DSM-5和ICD-10不包括AIR诊断。因此，我们根据经验将青少年分为基于AIR，躁狂，抑郁，违反规则和自我伤害行为的档案;检查哪些档案在三个样本中复制;并根据人口统计学和临床特征描述档案集。在协调了来自三个样本（n=679，n=392，n=634）的数据后，潜在特征分析（LPA）根据所有人报告的AIR，躁狂，抑郁，违规和自我伤害行为的测量结果将年轻人分配到特征中。每个样品的特征根据特征相似性分组。分析测试了诊断，性别，种族，年龄，功能和情绪严重程度的差异。八个配置文件的解决方案最适合。在样本中重复了七个特征：高AIR和自我伤害，较低的抑郁和躁狂评分;高AIR，躁狂症状和自我伤害;高抑郁症状;三个较小的集，高躁狂和抑郁症状和中度AIR;和两个高双相诊断率和双相家族史。两组患者的AIR和情绪症状都很高，受损最严重，合并症最高。分析支持AIR的经验定义，与情绪障碍分开。按AIR水平和情绪症状区分的配置文件集在人口统计学和诊断特征以及功能方面有所不同。重要的是，一组出现了高AIR但低情绪指标，ADHD和ODD的比例很高，但没有情绪障碍。
Aggression with impulsivity and reactivity (AIR) may distinguish a subset of youth from those with attention problems, rule-breaking behavior, or mood disorders, potentially with differential treatment response. Yet, DSM-5 and ICD-10 do not include an AIR diagnosis. Thus, we empirically grouped youths into profiles based on AIR, manic, depressive, rule-breaking, and self-harm behaviors; examined which profiles replicated across three samples; and characterized profile sets on demographic and clinical features. After harmonizing data from three samples (n=679, n=392, n=634), Latent Profile Analysis (LPA) assigned youth to profiles based on caregiver-reported measures of AIR, manic, depressive, rule-breaking, and self-harm behaviors. Profiles from each sample were grouped into sets based on profile similarity. Analyses tested differences in diagnoses, sex, and race, age, functioning, and mood severity. Eight-profile solutions fit best. Seven profiles replicated across samples: high AIR and self-harm, lower depressive and manic scores; high AIR, manic symptoms, and self-harm; high depression symptoms; three smaller sets with high manic and depressive symptoms and moderate AIR; and two high rates of bipolar diagnoses and family bipolar history. Two sets were high on both AIR and mood symptoms, were the most impaired, and had the highest comorbidity. Analyses support an empirical definition of AIR, separate from mood disorders. Profile sets distinguished by level of AIR and mood symptoms differed in demographic and diagnostic characteristics as well as functioning. Importantly, a set emerged with high AIR but low mood indicators and with high rates of ADHD and ODD, but not mood disorder.
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影响因子：
5.4
作者：
Goldstein BI;Birmaher B;Carlson GA;DelBello MP;Findling RL;Fristad M;Kowatch RA;Miklowitz DJ;Nery FG;Perez-Algorta G;Van Meter A;Zeni CP;Correll CU;Kim HW;Wozniak J;Chang KD;Hillegers M;Youngstrom EA
通讯作者：
Youngstrom EA
影响因子：
5.4
作者：
Findling, RL;Youngstrom, EA;Calabrese, JR
通讯作者：
Calabrese, JR
影响因子：
3.9
作者：
BYLES, J;BYRNE, C;OFFORD, DR
通讯作者：
OFFORD, DR
DOI：
10.1097/chi.0b013e31802f1454
发表时间：
2007-03-01
影响因子：
13.3
作者：
Jensen, Peter S.;Youngstrom, Eric A.;Vitiello, Benedetto
通讯作者：
Vitiello, Benedetto
影响因子：
2
作者：
Koenig, I. R.;Malley, J. D.;Ziegler, A.
通讯作者：
Ziegler, A.