Hydrogen Sulfide as a Potential Therapy for Heart Failure-Past, Present, and Future.
Hydrogen Sulfide as a Potential Therapy for Heart Failure-Past, Present, and Future.
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DOI:
10.3390/antiox10030485
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发表时间:
2021-03-19
期刊:
影响因子:
--
通讯作者:
Lefer DJ
中科院分区:
文献类型:
--
作者:
LaPenna KB;Polhemus DJ;Doiron JE;Hidalgo HA;Li Z;Lefer DJ
Hydrogen sulfide (H2S) is an endogenous, gaseous signaling molecule that plays a critical role in cardiac and vascular biology. H2S regulates vascular tone and oxidant defenses and exerts cytoprotective effects in the heart and circulation. Recent studies indicate that H2S modulates various components of metabolic syndrome, including obesity and glucose metabolism. This review will discuss studies exhibiting H2S -derived cardioprotective signaling in heart failure with reduced ejection fraction (HFrEF). We will also discuss the role of H2S in metabolic syndrome and heart failure with preserved ejection fraction (HFpEF).
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影响因子:
3.7
作者:
Bucci M;Papapetropoulos A;Vellecco V;Zhou Z;Zaid A;Giannogonas P;Cantalupo A;Dhayade S;Karalis KP;Wang R;Feil R;Cirino G
通讯作者:
Cirino G
影响因子:
37.8
作者:
Calvert JW;Elston M;Nicholson CK;Gundewar S;Jha S;Elrod JW;Ramachandran A;Lefer DJ
通讯作者:
Lefer DJ
影响因子:
16.2
作者:
Ford, ES
通讯作者:
Ford, ES
DOI:
10.3390/molecules22010063
发表时间:
2016-12-31
期刊:
Molecules (Basel, Switzerland)
影响因子:
--
作者:
Bełtowski J;Jamroz-Wiśniewska A
通讯作者:
Jamroz-Wiśniewska A
影响因子:
37.8
作者:
Kondo K;Bhushan S;King AL;Prabhu SD;Hamid T;Koenig S;Murohara T;Predmore BL;Gojon G Sr;Gojon G Jr;Wang R;Karusula N;Nicholson CK;Calvert JW;Lefer DJ
通讯作者:
Lefer DJ