Peek-a-boo: membrane hijacking and the pathogenesis of viral hepatitis.
Peek-a-boo: membrane hijacking and the pathogenesis of viral hepatitis.
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DOI:
10.1016/j.tim.2013.10.005
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发表时间:
2014-02
影响因子:
15.9
通讯作者:
Lemon, Stanley M.
中科院分区:
文献类型:
--
作者:
Feng, Zongdi;Lemon, Stanley M.
Historically, animal viruses have been classified on the basis of the presence or absence of an envelope – an external lipid bilayer membrane typically carrying one or more viral glycoproteins. However, growing evidence indicates that some ‘non-enveloped’ viruses circulate in the blood of infected individuals enveloped in host-derived membranes that provide protection from neutralizing antibodies. In this opinion piece, we discuss this novel strategy for virus survival and consider how it contributes to the pathogenesis of acute viral hepatitis. The acquisition of an envelope by ‘non-enveloped’ viruses profoundly influences their interaction with the host at both the cellular and system level, and challenges how we think about vaccine protection against these infections.
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影响因子:
6.7
作者:
Qu L;Feng Z;Yamane D;Liang Y;Lanford RE;Li K;Lemon SM
通讯作者:
Lemon SM
影响因子:
64.8
作者:
Feng Z;Hensley L;McKnight KL;Hu F;Madden V;Ping L;Jeong SH;Walker C;Lanford RE;Lemon SM
通讯作者:
Lemon SM
DOI:
10.1073/pnas.84.8.2497
发表时间:
1987-04-01
影响因子:
11.1
作者:
COHEN, JI;ROSENBLUM, B;PURCELL, RH
通讯作者:
PURCELL, RH
影响因子:
6.4
作者:
LEMON, SM;BINN, LN
通讯作者:
BINN, LN
DOI:
10.1002/path.1700480309
发表时间:
1939-05-01
期刊:
JOURNAL OF PATHOLOGY AND BACTERIOLOGY
影响因子:
--
作者:
Smith, W
通讯作者:
Smith, W