Mechanical Properties of the Developing Brain are Associated with Language Input and Vocabulary Outcome.
Mechanical Properties of the Developing Brain are Associated with Language Input and Vocabulary Outcome.
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发育中的大脑的机械特性与语言输入和词汇输出有关。
DOI：
10.1080/87565641.2022.2108425
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发表时间：
2022-08
影响因子：
1.5
通讯作者：
Johnson, Curtis L.
中科院分区：
文献类型：
--
作者：
Schneider, Julie M.;McIlvain, Grace;Johnson, Curtis L.
儿童在其环境中听到的语言质量与语言相关的大脑区域的发展有关，从而促进词汇知识。尽管这些环境影响提供了大量信息，但它如何改变神经组织的结构和随后的词汇结果仍然是未知的。目前的研究使用磁共振弹性成像（MRE）来研究儿童的语言环境如何构成脑组织力学特性的基础，其特征在于脑组织刚度和阻尼比，并促进词汇知识。25名5-7岁的儿童在与父母玩耍时录制了音频和视频。孩子们还完成了图片词汇任务（来自美国国立卫生研究院），并参加了核磁共振成像，其中磁共振成像和解剖图像被收购。高质量的输入与双侧额下回和右侧上级颞回的刚度相关，而词汇知识越多，右侧额下回的阻尼比越低。这些发现表明，神经组织组成的变化对环境的可塑性方面很敏感，而组织结构与词汇结果的关系更密切。值得注意的是，这些协会是独立的母亲的教育，这表明更近的措施，儿童的环境可能是来源的差异，神经组织结构的变化，在词汇的结果。
The quality of language that children hear in their environment is associated with the development of language-related brain regions, in turn promoting vocabulary knowledge. Although informative, it remains unknown how these environmental influences alter the structure of neural tissue and subsequent vocabulary outcomes. The current study uses magnetic resonance elastography (MRE) to examine how children’s language environments underlie brain tissue mechanical properties, characterized as brain tissue stiffness and damping ratio, and promote vocabulary knowledge. Twenty-five children, ages 5–7, had their audio and video recorded while engaging in a play session with their parents. Children also completed the Picture Vocabulary Task (from NIH Toolbox) and participated in an MRI, where MRE and anatomical images were acquired. Higher quality input was associated with greater stiffness in the bilateral inferior frontal gyrus and right superior temporal gyrus, whereas greater vocabulary knowledge was associated with lower damping ratio in the right inferior frontal gyrus. These findings suggest changes in neural tissue composition are sensitive to malleable aspects of the environment, whereas tissue organization is more strongly associated with vocabulary outcome. Notably, these associations were independent of maternal education, suggesting more proximal measures of a child’s environment may be the source of differences in neural tissue structure underlying variability in vocabulary outcomes.
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