Virus-PEDOT nanowires for biosensing.

Virus-PEDOT nanowires for biosensing.
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DOI:
10.1021/nl1025826
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发表时间:
2010-12-08
期刊:
影响因子:
10.8
通讯作者:
Weiss GA
Weiss GA
中科院分区:
材料科学1区
文献类型:
--
作者:
Arter JA;Taggart DK;McIntire TM;Penner RM;Weiss GA

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基于导电聚合物的电化学传感器和基于病毒的分子识别的不同领域为生物传感提供了许多优势。将M13噬菌体接枝到聚(3,4-乙撑二氧噻吩)(PEDOT)纳米线阵列中产生了导电聚合物和病毒的混合物。病毒掺入到PEDOT的聚合物主链中发生在通过光刻图案化纳米线电沉积(LPNE)的电聚合期间。由此产生的病毒-PEDOT纳米线阵列能够在生理相关缓冲液中对分析物进行实时、无试剂的电化学生物传感。
The separate fields of conducting polymer-based electrochemical sensors and virus-based molecular recognition offer numerous advantages for biosensing. Grafting M13 bacteriophage into an array of poly (3,4-ethylenedioxythiophene) (PEDOT) nanowires generated hybrids of conducting polymers and viruses. The virus incorporation into the polymeric backbone of PEDOT occurs during electropolymerization via lithographically patterned nanowire electrodeposition (LPNE). The resultant arrays of virus-PEDOT nanowires enable real-time, reagent-free electrochemical biosensing of analytes in physiologically relevant buffers.
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