Virus-PEDOT nanowires for biosensing.
Virus-PEDOT nanowires for biosensing.
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DOI:
10.1021/nl1025826
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发表时间:
2010-12-08
期刊:
影响因子:
10.8
通讯作者:
Weiss GA
中科院分区:
文献类型:
--
作者:
Arter JA;Taggart DK;McIntire TM;Penner RM;Weiss GA
The separate fields of conducting polymer-based electrochemical sensors and virus-based molecular recognition offer numerous advantages for biosensing. Grafting M13 bacteriophage into an array of poly (3,4-ethylenedioxythiophene) (PEDOT) nanowires generated hybrids of conducting polymers and viruses. The virus incorporation into the polymeric backbone of PEDOT occurs during electropolymerization via lithographically patterned nanowire electrodeposition (LPNE). The resultant arrays of virus-PEDOT nanowires enable real-time, reagent-free electrochemical biosensing of analytes in physiologically relevant buffers.
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