Global and regional estimates of cancer mortality and incidence by site: II. Results for the global burden of disease 2000.
Global and regional estimates of cancer mortality and incidence by site: II. Results for the global burden of disease 2000.
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按地点划分的全球和区域癌症死亡率和发病率估计：II。 2000 年全球疾病负担的结果。
DOI：
10.1186/1471-2407-2-37
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发表时间：
2002-12-26
期刊：
影响因子：
3.8
通讯作者：
Murray, CJL
中科院分区：
文献类型：
--
作者：
Shibuya, K;Mathers, CD;Boschi-Pinto, C;Lopez, AD;Murray, CJL
仅死亡率估计不足以了解癌症负担的真实程度。我们提出了按地点划分的死亡率和发病率的详细估计，作为未来 2000 年全球疾病负担研究的癌症负担估计的基础。按地区划分的所有恶性肿瘤的年龄和性别死亡率范围是通过对国家生命表和死因的分析得出的。我们根据生命记录和癌症生存模型估计了特定地点的癌症死亡率分布。按地点划分的区域癌症死亡率是通过根据死亡率分布分解区域癌症死亡率范围来估计的。估计的发病率与死亡率之比用于反算按地点划分的最终癌症发病率估计值。 2000年，癌症导致超过700万人死亡（占总死亡率的13%），2000年全世界新发癌症病例超过1000万例。超过60%的癌症死亡和大约一半的新发病例发生在发展中地区。肺癌是世界上最常见的癌症，其次是胃癌、肝癌、结肠癌、直肠癌和乳腺癌。不同地区的特定地点癌症死亡率和发病率分布存在显着差异。尽管存在地区差异，但最常见的癌症是可以预防的。通过考虑死亡率和发病率来估计癌症负担是确定研究重点和政策制定的重要步骤。与癌症干预成本数据相结合时，它还可以用于确定优先事项。
Mortality estimates alone are not sufficient to understand the true magnitude of cancer burden. We present the detailed estimates of mortality and incidence by site as the basis for the future estimation of cancer burden for the Global Burden of Disease 2000 study. Age- and sex- specific mortality envelope for all malignancies by region was derived from the analysis of country life-tables and cause of death. We estimated the site-specific cancer mortality distributions from vital records and cancer survival model. The regional cancer mortality by site is estimated by disaggregating the regional cancer mortality envelope based on the mortality distribution. Estimated incidence-to-mortality rate ratios were used to back calculate the final cancer incidence estimates by site. In 2000, cancer accounted for over 7 million deaths (13% of total mortality) and there were more than 10 million new cancer cases world wide in 2000. More than 60% of cancer deaths and approximately half of new cases occurred in developing regions. Lung cancer was the most common cancers in the world, followed by cancers of stomach, liver, colon and rectum, and breast. There was a significant variations in the distribution of site-specific cancer mortality and incidence by region. Despite a regional variation, the most common cancers are potentially preventable. Cancer burden estimation by taking into account both mortality and morbidity is an essential step to set research priorities and policy formulation. Also it can used for setting priorities when combined with data on costs of interventions against cancers.
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影响因子：
3.8
作者：
Mathers CD;Shibuya K;Boschi-Pinto C;Lopez AD;Murray CJ
通讯作者：
Murray CJ
影响因子：
6.4
作者：
BAYO, S;PARKIN, DM;SANGARE, S
通讯作者：
SANGARE, S
DOI：
10.1034/j.1600-0412.2002.810512.x
发表时间：
2002-05-01
影响因子：
4.3
作者：
Bergmark, K;Åvall-Lundqvist, E;Steineck, G
通讯作者：
Steineck, G
影响因子：
14.5
作者：
Parkin, DM
通讯作者：
Parkin, DM
影响因子：
13.6
作者：
Boschmonar, MCG;Chaviano, PJJ;Sankaranarayanan, R
通讯作者：
Sankaranarayanan, R