Rare cell separation and analysis by magnetic sorting.

Rare cell separation and analysis by magnetic sorting.
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DOI:
10.1021/ac200550d
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发表时间:
2011-11-01
影响因子:
7.4
通讯作者:
Chamers, Jeffrey J.
Chamers, Jeffrey J.
中科院分区:
化学1区
文献类型:
--
作者:
Zborowski, Maciej;Chamers, Jeffrey J.

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使用磁力分离和/或分离稀有细胞是常用的,并且在从用于进一步研究的简单样品制备到FDA批准的临床诊断测试的范围内使用。这种增长是获得用于分子分析的同质稀有细胞的需求以及永磁体功率的急剧增加的结果,永磁体甚至允许基于固有磁矩分离一些未标记的细胞,例如疟疾寄生虫感染的红细胞。
The separation and or isolation of rare cells using magnetic forces is commonly used and growing in use ranging from simple sample prep for further studies to a FDA approved, clinical diagnostic test. This grown is the result of both the demand to obtain homogeneous rare cells for molecular analysis and the dramatic increases in the power of permanent magnets that even allow the separation of some unlabeled cells based on intrinsic magnetic moments, such as malaria parasite-infected red blood cells.
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