Constituents of Psoralea corylifolia Fruits and Their Effects on Methicillin-Resistant Staphylococcus aureus.
Constituents of Psoralea corylifolia Fruits and Their Effects on Methicillin-Resistant Staphylococcus aureus.
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DOI：
10.3390/molecules200712500
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发表时间：
2015-07-09
期刊：
影响因子：
--
通讯作者：
Hatano T
中科院分区：
文献类型：
--
作者：
Cui Y;Taniguchi S;Kuroda T;Hatano T
从补骨脂果实中分离得到2个新黄酮类化合物，分别命名为巴古黄酮（1）和巴古黄酮酮（2），并鉴定了15个已知化合物的结构。还检查了分离的化合物对耐甲氧西林金黄色葡萄球菌的作用。我们发现，两种化合物，isobavachalcone（10）和bakuchiol（12），显示出显着的抗菌作用的MRSA菌株检查。然后对主要成分（包括抗MRSA成分）进行定量。结果表明，在紫堇果实的乙酸乙酯提取物中，被测化合物的含量为1.26%~ 16.49%（w/w）。
Two new flavonoids, bakuisoflavone (1) and bakuflavanone (2), together with 15 known compounds, were isolated from the fruits of Psoralea corylifolia, and their structures were characterized by spectroscopic data. The effects of the isolated compounds on methicillin-resistant Staphylococcus aureus were also examined. We found that two compounds, isobavachalcone (10) and bakuchiol (12), showed noticeable antibacterial effects on the MRSA strains examined. Quantitation of the major constituents, including anti-MRSA constituents, was then performed. The results showed individual contents of 1.26%–16.49% (w/w) among the examined compounds in the ethyl acetate extract from P. corylifolia fruits.
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影响因子：
3.5
作者：
Yin, S;Fan, CQ;Yue, JM
通讯作者：
Yue, JM
影响因子：
4.1
作者：
Xiao, Guodong;Li, Guowen;Wang, Zhengtao
通讯作者：
Wang, Zhengtao
影响因子：
7.9
作者：
Lim, Sun-Hye;Ha, Tae-Youl;Kim, Suna
通讯作者：
Kim, Suna
影响因子：
3.8
作者：
Masuda, T;Takasugi, M;Anetai, M
通讯作者：
Anetai, M
DOI：
10.3390/molecules190913027
发表时间：
2014-08-25
期刊：
Molecules (Basel, Switzerland)
影响因子：
--
作者：
Eerdunbayaer;Orabi MA;Aoyama H;Kuroda T;Hatano T
通讯作者：
Hatano T