Distinct branches of the N-end rule pathway modulate the plant immune response.
Distinct branches of the N-end rule pathway modulate the plant immune response.
复制标题
N 端规则途径的不同分支调节植物免疫反应。
DOI:
10.1111/nph.15387
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发表时间:
2019
期刊:
影响因子:
--
通讯作者:
Vicente J
中科院分区:
文献类型:
--
作者:
Vicente J
The N‐end rule pathway is a highly conserved constituent of the ubiquitin proteasome system, yet little is known about its biological roles.Here we explored the role of the N‐end rule pathway in the plant immune response. We investigated the genetic influences of components of the pathway and known protein substrates on physiological, biochemical and metabolic responses to pathogen infection.We show that the glutamine (Gln) deamidation and cysteine (Cys) oxidation branches are both components of the plant immune system, through the E3 ligase PROTEOLYSIS (PRT)6. InArabidopsis thalianaGln‐specific amino‐terminal (Nt)‐amidase (NTAQ1) controls the expression of specific defence‐response genes, activates the synthesis pathway for the phytoalexin camalexin and influences basal resistance to the hemibiotroph pathogenPseudomonas syringaepvtomato(Pst). The Nt‐Cys ETHYLENE RESPONSE FACTOR VII transcription factor substrates enhance pathogen‐induced stomatal closure. Transgenic barley with reducedHvPRT6expression showed enhanced resistance toPs. japonicaandBlumeria graminisf. sp.hordei, indicating a conserved role of the pathway.We propose that that separate branches of the N‐end rule pathway act as distinct components of the plant immune response in flowering plants.
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影响因子:
4.6
作者:
de Marchi R;Sorel M;Mooney B;Fudal I;Goslin K;Kwaśniewska K;Ryan PT;Pfalz M;Kroymann J;Pollmann S;Feechan A;Wellmer F;Rivas S;Graciet E
通讯作者:
Graciet E
影响因子:
13.8
作者:
Lehmeyer, Mona;Kanofsky, Konstantin;Hehl, Reinhard
通讯作者:
Hehl, Reinhard
影响因子:
7.2
作者:
Ferrari, S;Plotnikova, JM;Ausubel, FM
通讯作者:
Ausubel, FM
影响因子:
11.6
作者:
Xu, Fang;Huang, Yan;Li, Xin
通讯作者:
Li, Xin
影响因子:
64.8
作者:
Asai, T;Tena, G;Sheen, J
通讯作者:
Sheen, J