Social conflict in centimeter-and global-scale populations of the bacterium Myxococcus xanthus.
Social conflict in centimeter-and global-scale populations of the bacterium Myxococcus xanthus.
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DOI：
10.1016/j.cub.2009.08.061
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发表时间：
2009-11-03
期刊：
影响因子：
--
通讯作者：
Velicer GJ
中科院分区：
文献类型：
--
作者：
Vos M;Velicer GJ
参与合作行为的微生物之间的社会相互作用在实验室环境中得到了很好的研究，但对最初合作的微生物在自然界中多样化为社会冲突基因型的规模知之甚少。捕食性土壤细菌黄色粘球菌通过合作形成多细胞子实体来响应饥饿，其中一部分种群分化为抗应激孢子。天然M. Xanthus种群是空间结构化的，并且来自遥远起源的遗传上不同的分离物表现出显著的发育拮抗作用，其减少嵌合子实体中的孢子产生。在这里，我们表明，遗传相似的分离M。当在发育中混合时，来自厘米级种群的xanthus也表现出强烈和普遍的拮抗作用。嵌合体的负反应不那么强烈，平均而言，在当地菌株比全球分离株，虽然没有显着的相关性，发现在多位点序列分型（MLST）位点的遗传距离和竞争对手之间的社会不对称程度。测试自我/非自我歧视在植物群集揭示了巨大的多样性不同的自我识别类型，即使在相同的MLST基因型。这种非自我排斥可能有助于将合作的好处导向不同人群中的近亲，而在这些人群中，邻居之间发生社会冲突的可能性很高。
Social interactions among microbes that engage in cooperative behaviours are well studied in laboratory contexts, but little is known about the scales at which initially cooperative microbes diversify into socially conflicting genotypes in nature. The predatory soil bacterium Myxococcus xanthus responds to starvation by cooperatively forming multi-cellular fruiting bodies in which a portion of the population differentiates into stress-resistant spores. Natural M. xanthus populations are spatially structured and genetically divergent isolates from distant origins exhibit striking developmental antagonisms that decrease spore production in chimaeric fruiting bodies. Here we show that genetically similar isolates of M. xanthus from a centimeter-scale population also exhibit strong and pervasive antagonisms when mixed in development. Negative responses to chimerism were less intense, on average, among local strains than among global isolates, although no significant correlation was found between genetic distance at multi-locus sequence typing (MLST) loci and the degree of social asymmetry between competitors. A test for self/non-self discrimination during vegetative swarming revealed a great diversity of distinct self-recognition types even among identical MLST genotypes. Such non-self exclusion may serve to direct the benefits of cooperation to close kin within diverse populations in which the probability of social conflict among neighbours is high.
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DOI：
10.1073/pnas.0702723104
发表时间：
2007-05-22
影响因子：
11.1
作者：
Gilbert, Owen M.;Foster, Kevin R.;Queller, David C.
通讯作者：
Queller, David C.
影响因子：
9.4
作者：
Pfaller, MA;Mujeeb, I;Doern, GV
通讯作者：
Doern, GV
影响因子：
64.8
作者：
Mehdiabadi, Natasha J.;Jack, Chandra N.;Strassmann, Joan E.
通讯作者：
Strassmann, Joan E.
影响因子：
2.5
作者：
APPLEBY, MC
通讯作者：
APPLEBY, MC
DOI：
10.1126/science.1160033
发表时间：
2008-07-11
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Gibbs KA;Urbanowski ML;Greenberg EP
通讯作者：
Greenberg EP