Extending the developmental origins of disease model: Impact of preconception stress exposure on offspring neurodevelopment.
Extending the developmental origins of disease model: Impact of preconception stress exposure on offspring neurodevelopment.
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DOI：
10.1002/dev.21773
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发表时间：
2018-11
影响因子：
2.2
通讯作者：
Mbayiwa K
中科院分区：
文献类型：
--
作者：
Keenan K;Hipwell AE;Class QA;Mbayiwa K
The concept of the developmental origins of health and disease via prenatal programming has informed many etiologic models of health and development. Extensive experimental research in non-human animal models has revealed the impact of in utero exposure to stress on fetal development and neurodevelopment later in life. Stress exposure, however, is unlikely to occur de novo following conception, and pregnancy health is not independent of the health of the system prior to conception. For these reasons, the preconception period is emerging as an important new focus for research on adverse birth outcomes and offspring neurodevelopment. In this review we summarize the existing evidence for the role of preconception stress exposure on pregnancy health and offspring neurodevelopment across species and discuss the implications of this model for addressing health disparities in obstetrics and offspring outcomes.
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影响因子：
3.3
作者：
Class QA;Lichtenstein P;Långström N;D'Onofrio BM
通讯作者：
D'Onofrio BM
影响因子：
3.1
作者：
Bock, Joerg;Poeschel, Julia;Poeggel, Gerd
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Poeggel, Gerd
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3.7
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Stafford B
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10.6
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Bergman, Kristin;Sarkar, Pampa;Glover, Vivette;O'Connor, Thomas G.
通讯作者：
O'Connor, Thomas G.
影响因子：
6.9
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Colman, I.;Jones, P. B.;Croudace, T. J.
通讯作者：
Croudace, T. J.