T regulatory cells and transplantation tolerance.
T regulatory cells and transplantation tolerance.
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DOI:
10.1016/j.trre.2010.04.002
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发表时间:
2010-07
期刊:
影响因子:
--
通讯作者:
Zheng XX
中科院分区:
文献类型:
--
作者:
Gorantla VS;Schneeberger S;Brandacher G;Sucher R;Zhang D;Lee WP;Zheng XX
Despite the development of successful immunosuppression protocols and tremendous improvement in short-term graft survival rates, the problem of chronic graft loss remains the bane of clinical transplantation. The induction and maintenance of transplantation tolerance is the “Holy grail” of transplantation. The recent identification and characterization of regulatory T cells (T regs) has opened up exciting opportunities for tolerance induction, immunotherapy and immunomodulation in transplantation. This review focuses on current understanding of regulatory T cells and their role in transplantation tolerance.
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影响因子:
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作者:
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通讯作者:
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DOI:
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发表时间:
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期刊:
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