Arm blood flow and metabolism during arm and combined arm and leg exercise in humans

Arm blood flow and metabolism during arm and combined arm and leg exercise in humans
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人类手臂和手臂和腿部联合运动期间的手臂血流量和新陈代谢

DOI:
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发表时间:
2002
期刊:
Journal of Physiology
影响因子:
--
通讯作者:
Niels H. Secher
Niels H. Secher
中科院分区:
--
文献类型:
--
作者:
S. Volianitis;Niels H. Secher

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心血管对多组骨骼肌运动的反应表明,手臂运动可能会减少腿部血流量。这项研究评估了腿部的剧烈运动是否会对手臂血流量 (Qarm) 和氧气消耗量 (V̇O2,arm) 产生类似的影响。 10 名健康男性受试者(年龄 21 ± 1 岁;平均值 ± S.D.)以最大手臂工作能力的 80% 进行手臂摇动(A 试验),并以最大腿部工作能力的 60% 进行手臂摇动和骑自行车(A + L 试验)。联合试验的最大努力持续 5-6 分钟。通过热稀释腋静脉和动脉和静脉血样进行 Qarm 测量,可以计算 V̇O2,arm。在联合试验期间,Qarm 比摇臂转动期间的值 (3.00 ± 0.46 l min−1) 减少了 0.58 ± 0.25 l min−1 (19.1 ± 3.0 %,P < 0.05)。动静脉 O2 差异从手臂试验期间的 122 ± 15 ml l−1 增加到联合试验期间的 150 ± 21 ml l−1 (P < 0.05)。因此,随着手臂去甲肾上腺素溢出从 7.5 ± 3.5 增加到 13.8 ±,V̇O2,arm (0.45 ± 0.06 l min−1) 减少了 9.6 ± 6.3 % (P < 0.05),手臂血管电导从 27 ± 4 减少到 23 ± 3 ml min−1 (mmHg)−1 (P < 0.05)。 4.2 nmol min−1 (P < 0.05)。数据表明,在人类最大程度的全身运动过程中,手臂血管收缩的程度会影响工作骨骼肌的氧气输送和利用。
The cardiovascular response to exercise with several groups of skeletal muscle suggests that work with the arms may decrease leg blood flow. This study evaluated whether intense exercise with the legs would have a similar effect on arm blood flow (Qarm) and O2 consumption (V̇O2,arm). Ten healthy male subjects (age 21 ± 1 year; mean ± S.D.) performed arm cranking at 80 % of maximum arm work capacity (A trial) and combined arm cranking with cycling at 60 % of maximum leg work capacity (A + L trial). The combined trial was a maximum effort for 5‐6 min. Qarm measurement by thermodilution in the axilliary vein and arterial and venous blood samples permitted calculation of V̇O2,arm. During the combined trial, Qarm was reduced by 0.58 ± 0.25 l min−1 (19.1 ± 3.0 %, P < 0.05) from the value during arm cranking (3.00 ± 0.46 l min−1). The arterio‐venous O2 difference increased from 122 ± 15 ml l−1 during the arm trial to 150 ± 21 ml l−1 (P < 0.05) during the combined trial. Thus, V̇O2,arm (0.45 ± 0.06 l min−1) was reduced by 9.6 ± 6.3 % (P < 0.05) and arm vascular conductance from 27 ± 4 to 23 ± 3 ml min−1 (mmHg)−1 (P < 0.05) as noradrenaline spillover from the arm increased from 7.5 ± 3.5 to 13.8 ± 4.2 nmol min−1 (P < 0.05). The data suggest that during maximal whole body exercise in humans, arm vasoconstriction is established to an extent that affects oxygen delivery to and utilisation by working skeletal muscles.
DOI: 10.1152/jappl.1997.82.5.1573
发表时间: 1997-05-01
影响因子: 3.3
作者:
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DOI: 10.1152/jappl.1993.75.4.1911
发表时间: 1993
期刊: Journal of applied physiology (Bethesda, Md. : 1985)
影响因子: --
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发表时间: 1997
期刊: The American journal of physiology
影响因子: --
作者:
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