Topology of blood transport in the human left ventricle by novel processing of Doppler echocardiography.

Topology of blood transport in the human left ventricle by novel processing of Doppler echocardiography.
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DOI:
10.1007/s10439-013-0853-z
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发表时间:
2013-12
影响因子:
3.8
通讯作者:
Shadden, Shawn C.
Shadden, Shawn C.
中科院分区:
工程技术2区
文献类型:
--
作者:
Hendabadi, Sahar;Bermejo, Javier;Benito, Yolanda;Yotti, Raquel;Fernandez-Aviles, Francisco;del Alamo, Juan C.;Shadden, Shawn C.

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应用多普勒超声心动图数据的新处理方法,研究了6例扩张型心肌病患者和6例健康志愿者左心室(LV)的血液转运。彩色多普勒超声心动图重建左室心尖长轴双向速度场图。得到的速度场数据被用来进行拉格朗日相干结构(LCS)的基于概率的计算。LCS被证明可以揭示多次心跳中从心脏注入和排出的血液的边界。这使得能够定性和定量评估血液转运模式和在LV中的停留时间。报告了LV淤滞的定量评估,以及E波和A波充盈的LV涡旋形成的表征。
Novel processing of Doppler-echocardiography data was used to study blood transport in the left ventricle (LV) of 6 patients with dilated cardiomyopathy and 6 healthy volunteers. Bi-directional velocity field maps in the apical long axis of the LV were reconstructed from color-Doppler echocardiography. Resulting velocity field data were used to perform trajectory-based computation of Lagrangian coherent structures (LCS). LCS were shown to reveal the boundaries of blood injected and ejected from the heart over multiple beats. This enabled qualitative and quantitive assessments of blood transport patterns and residence times in the LV. Quantitative assessments of stasis in the LV are reported, as well as characterization of LV vortex formations from E-wave and A-wave filling.
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