Does quantification have a role to play in the future of bone SPECT?
Does quantification have a role to play in the future of bone SPECT?
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DOI：
10.1186/s41824-019-0054-6
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发表时间：
2019-05-03
影响因子：
1.7
通讯作者：
Dickson J
中科院分区：
文献类型：
--
作者：
Ross JC;Vilić D;Sanderson T;Vöö S;Dickson J
然而，核医学报告有一个视觉基础：报告者根据他们所看到的主观地将患者的病情分为多个离散类别之一。增加定量结果，如标准化摄取值（SUV），将提供对摄取性质的数值洞察，提供更大的客观性，并可能改善患者管理。特别是对于骨显像，定量可以通过帮助区分正常和异常摄取来提高诊断的准确性。获得定量数据也可能提高我们的能力，以确定病变，分层和监测病人的条件，并进行可靠的放射性核素治疗剂量测定。但是，是否有足够的证据表明，我们作为一个社区，应该作出更多的努力，在常规临床实践中实施定量骨SPECT？我们通过PubMed搜索引擎进行了多次查询，以促进骨SPECT定量的当前状态的横截面审查。高被引论文的评估更加集中，以审查他们的结论。越来越多的作者报告了SUVmax等指标的发现。尽管对该领域的兴趣总体上仍然很高，但定量骨SPECT的临床实施速度仍然很慢，并且在我们忘乎所以之前需要进行大量的验证。
Routinely, there is a visual basis to nuclear medicine reporting: a reporter subjectively places a patient’s condition into one of multiple discrete classes based on what they see. The addition of a quantitative result, such as a standardised uptake value (SUV), would provide a numerical insight into the nature of uptake, delivering greater objectivity, and perhaps improved patient management. For bone scintigraphy in particular quantification could increase the accuracy of diagnosis by helping to differentiate normal from abnormal uptake. Access to quantitative data might also enhance our ability to characterise lesions, stratify and monitor patients’ conditions, and perform reliable dosimetry for radionuclide therapies. But is there enough evidence to suggest that we, as a community, should be making more effort to implement quantitative bone SPECT in routine clinical practice? We carried out multiple queries through the PubMed search engine to facilitate a cross-sectional review of the current status of bone SPECT quantification. Highly cited papers were assessed in more focus to scrutinise their conclusions. An increasing number of authors are reporting findings in terms of metrics such as SUVmax. Although interest in the field in general remains high, the rate of clinical implementation of quantitative bone SPECT remains slow and there is a significant amount of validation required before we get carried away.
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影响因子：
3.2
作者：
Beck M;Sanders JC;Ritt P;Reinfelder J;Kuwert T
通讯作者：
Kuwert T
影响因子：
3.2
作者：
Nakahara T;Daisaki H;Yamamoto Y;Iimori T;Miyagawa K;Okamoto T;Owaki Y;Yada N;Sawada K;Tokorodani R;Jinzaki M
通讯作者：
Jinzaki M
DOI：
10.1007/s00259-009-1334-3
发表时间：
2010-04-01
影响因子：
9.1
作者：
Helyar, Vincent;Mohan, Hosahalli K.;Fogelman, Ignac
通讯作者：
Fogelman, Ignac
DOI：
10.1016/j.remn.2017.01.003
发表时间：
2017-07-01
影响因子：
1.2
作者：
Lopez Buitrago, D. F.;Ruiz Bptero, J.;Sabogal, A.
通讯作者：
Sabogal, A.
影响因子：
1.5
作者：
O'Mahoney, Eoin;Murray, Iain
通讯作者：
Murray, Iain