Versatile Physiological Functions of Plant GSK3-Like Kinases.

Versatile Physiological Functions of Plant GSK3-Like Kinases.
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植物 GSK3 样激酶的多功能生理功能。

DOI:
10.3390/genes12050697
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发表时间:
2021-05-08
期刊:
影响因子:
3.5
通讯作者:
Li J
Li J
中科院分区:
生物学3区
文献类型:
--
作者:
Mao J;Li W;Liu J;Li J

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植物糖原合成酶激酶3(GSK 3)样激酶是高度保守的蛋白丝氨酸/苏氨酸激酶,分为四个亚家族。与它们的哺乳动物同源物相似,这些激酶在正常生长条件下是组成型活性的,但在响应不同的发育和环境信号时变得失活。自20世纪90年代初首次发现以来,人们进行了许多生化和遗传研究,以研究其在各种植物物种中的生理功能。这些研究表明植物GSK 3样激酶是一种多功能激酶,不仅参与多种植物生长发育过程,而且参与多种植物胁迫反应。在这里,我们总结了我们目前的了解,多功能的植物GSK 3样激酶沿着的生理功能,以及他们的确认和潜在的底物。
The plant glycogen synthase kinase 3 (GSK3)-like kinases are highly conserved protein serine/threonine kinases that are grouped into four subfamilies. Similar to their mammalian homologs, these kinases are constitutively active under normal growth conditions but become inactivated in response to diverse developmental and environmental signals. Since their initial discoveries in the early 1990s, many biochemical and genetic studies were performed to investigate their physiological functions in various plant species. These studies have demonstrated that the plant GSK3-like kinases are multifunctional kinases involved not only in a wide variety of plant growth and developmental processes but also in diverse plant stress responses. Here we summarize our current understanding of the versatile physiological functions of the plant GSK3-like kinases along with their confirmed and potential substrates.
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发表时间: 2014-11
影响因子: 3.8
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