Melanocortin control of energy balance: evidence from rodent models.
Melanocortin control of energy balance: evidence from rodent models.
复制标题
黑皮质素对能量平衡的控制：来自啮齿动物模型的证据。
DOI：
10.1007/s00018-011-0707-5
复制
发表时间：
2011-08
影响因子：
8
通讯作者：
Bence, Kendra K.
中科院分区：
文献类型：
--
作者：
De Jonghe, Bart C.;Hayes, Matthew R.;Bence, Kendra K.
Regulation of energy balance is extremely complex, and involves multiple systems of hormones, neurotransmitters, receptors, and intracellular signals. As data have accumulated over the last two decades, the CNS melanocortin system is now identified as a prominent integrative network of energy balance controls in the mammalian brain. Here, we will review findings from rat and mouse models, which have provided an important framework in which to study melanocortin function. Perhaps most importantly, this review attempts for the first time to summarize recent advances in our understanding of the intracellular signaling pathways thought to mediate the action of melanocortin neurons and peptides in control of long term energy balance. Special attention will be paid to the roles of MC4R/MC3R, as well as downstream neurotransmitters within forebrain and hindbrain structures that illustrate the distributed control of melanocortin signaling in energy balance. In addition, distinctions and controversy between rodent species will be discussed.
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影响因子：
29
作者：
Al-Qassab H;Smith MA;Irvine EE;Guillermet-Guibert J;Claret M;Choudhury AI;Selman C;Piipari K;Clements M;Lingard S;Chandarana K;Bell JD;Barsh GS;Smith AJ;Batterham RL;Ashford ML;Vanhaesebroeck B;Withers DJ
通讯作者：
Withers DJ
DOI：
10.1152/ajpregu.00604.2003
发表时间：
2004-07-01
影响因子：
2.8
作者：
Blevins, JE;Schwartz, MW;Baskin, DG
通讯作者：
Baskin, DG
影响因子：
15.9
作者：
Banno, Ryoichi;Zimmer, Derek;Bence, Kendra K.
通讯作者：
Bence, Kendra K.
影响因子：
4.8
作者：
Brito, Marcia N.;Brito, Nilton A.;Bartness, Timothy J.
通讯作者：
Bartness, Timothy J.
影响因子：
--
作者：
Blevins JE;Baskin DG
通讯作者：
Baskin DG