Hypothalamic-brainstem circuits controlling eating.
Hypothalamic-brainstem circuits controlling eating.
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DOI：
10.1159/000264401
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发表时间：
2010
影响因子：
--
通讯作者：
Baskin DG
中科院分区：
文献类型：
--
作者：
Blevins JE;Baskin DG
It is now axiomatic that neurons in the hypothalamic arcuate nucleus have a primary role in responding to changes in circulating levels of leptin and transmitting signals to downstream circuits that influence eating and energy expenditure. Signals generated from the gastrointestinal tract during meals reach the brainstem, via the vagus nerve and other routes, and impinge on neural circuits that influence the timing and size of meals and amount of food consumed. One of the mechanisms by which leptin exerts its anorexic effects is by increasing the effectiveness of intestinal signals that cause satiation during a meal. It is clear that the effects of gut satiation signals such as CCK can be amplified by leptin acting in the CNS, and in the arcuate nucleus in particular. The present article describes the state of our knowledge about specific neural circuits between the hypothalamus and brainstem that play a role in the interaction of leptin and meal-control signals to control food intake.
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DOI：
10.1152/ajpregu.00604.2003
发表时间：
2004-07-01
影响因子：
2.8
作者：
Blevins, JE;Schwartz, MW;Baskin, DG
通讯作者：
Baskin, DG
影响因子：
2.9
作者：
Emond, M;Ladenheim, EE;Moran, TH
通讯作者：
Moran, TH
影响因子：
3
作者：
ARLETTI, R;BENELLI, A;BERTOLINI, A
通讯作者：
BERTOLINI, A
影响因子：
4.8
作者：
McMinn, JE;Sindelar, DK;Schwartz, MW
通讯作者：
Schwartz, MW
影响因子：
1.9
作者：
KAPLAN, JM;SEELEY, RJ;GRILL, HJ
通讯作者：
GRILL, HJ