Relationship between neutrophil/lymphocyte ratio and epicardial fat tissue thickness in patients with newly diagnosed hypertension.
Relationship between neutrophil/lymphocyte ratio and epicardial fat tissue thickness in patients with newly diagnosed hypertension.
复制标题
DOI：
10.1177/0300060517749130
复制
发表时间：
2018-03
期刊：
影响因子：
--
通讯作者：
Ede H
中科院分区：
文献类型：
--
作者：
Derya MA;Demir V;Ede H
心外膜脂肪组织厚度（EFT）和中性粒细胞/淋巴细胞比率（NLR）与动脉粥样硬化相关。很少有研究集中在这些参数之间的关系，在新诊断的高血压患者。在这项研究中，我们探讨了EFT和NLR的新诊断的高血压患者的24小时动态血压监测（ABPM）检测。80例根据ABPM结果诊断为高血压的无慢性疾病的连续患者和80例其他健康受试者入组研究。超声心动图测量每个参与者的EFT。C-反应蛋白（CRP）浓度和NLR从静脉血样本中测定。高血压组的24小时平均收缩压显著高于对照组（分别为143±17和117±7 mmHg）。两组之间在年龄、性别或体重指数方面没有显著差异。高血压组EFT、NLR、CRP浓度均显著高于对照组。此外，在对照组和高血压组中，EFT与NLR均呈显著正相关。新诊断高血压患者EFT和NLR明显高于健康对照组。
Epicardial fat tissue thickness (EFT) and the neutrophil/lymphocyte ratio (NLR) are associated with atherosclerosis. Few studies have focused on the relationship between these parameters in patients with newly diagnosed hypertension. In this study, we examined the relationship between EFT and the NLR in patients with newly diagnosed hypertension detected by 24-hour ambulatory blood pressure monitoring (ABPM). Eighty consecutive patients without chronic illness who were diagnosed with hypertension according to ABPM results and 80 otherwise healthy subjects were enrolled in the study. EFT of each participant was measured echocardiographically. The C-reactive protein (CRP) concentration and NLR were measured from venous blood samples. The 24-hour average systolic blood pressure was significantly higher in the hypertension group than in the control group (143±17 vs. 117±7 mmHg, respectively). There were no significant differences in age, sex, or body mass index between the two groups. EFT, the NLR, and the CRP concentration were significantly higher in the hypertension group than control group. Additionally, a significantly positive correlation between EFT and the NLR was found in both the control group and hypertension group. A higher EFT and NLR were detected in patients with newly diagnosed hypertension than in healthy subjects.
登录
查看更多内容
影响因子：
7.3
作者：
Mozos I;Malainer C;Horbańczuk J;Gug C;Stoian D;Luca CT;Atanasov AG
通讯作者：
Atanasov AG
影响因子：
3.6
作者：
Yumuk V;Tsigos C;Fried M;Schindler K;Busetto L;Micic D;Toplak H;Obesity Management Task Force of the European Association for the Study of Obesity
通讯作者：
Obesity Management Task Force of the European Association for the Study of Obesity
影响因子：
2.4
作者：
Ferdinand, Keith C.;Nasser, Samar A.
通讯作者：
Nasser, Samar A.
DOI：
10.1016/j.echo.2015.05.002
发表时间：
2015-07-01
影响因子：
6.5
作者：
Marwick, Thomas H.;Gillebert, Thierry C.;Zamorano, Jose L.
通讯作者：
Zamorano, Jose L.
影响因子：
2.1
作者：
Salazar J;Luzardo E;Mejías JC;Rojas J;Ferreira A;Rivas-Ríos JR;Bermúdez V
通讯作者：
Bermúdez V