MetaboLights: towards a new COSMOS of metabolomics data management.

MetaboLights: towards a new COSMOS of metabolomics data management.
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DOI:
10.1007/s11306-012-0462-0
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发表时间:
2012-10
期刊:
影响因子:
3.6
通讯作者:
Griffin, Julian L.
Griffin, Julian L.
中科院分区:
医学3区
文献类型:
--
作者:
Steinbeck, Christoph;Conesa, Pablo;Haug, Kenneth;Mahendraker, Tejasvi;Williams, Mark;Maguire, Eamonn;Rocca-Serra, Philippe;Sansone, Susanna-Assunta;Salek, Reza M.;Griffin, Julian L.

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欧洲和美国正在出现令人兴奋的资助计划,用于代谢组学数据的生产,存储,传播和分析。这是基于世界各地丰富的资源生态系统,在过去十年中已经建立,包括但不限于日本的MassBank和加拿大的人类代谢组数据库等资源。现在,欧洲生物信息学研究所推出了MetaboLights,这是一个代谢组学实验和相关元数据的数据库(http://www.ebi.ac.uk/metabolights)。它是第一个全面的,跨物种,跨平台的代谢组学数据库,由分子生物学中主要的开放获取数据提供商之一维护。今年10月,欧洲COSMOS联盟将开始其代谢组学数据标准化、出版和传播工作流程的工作。美国国立卫生研究院正在建立6-8个代谢组学服务核心以及国家代谢组学储存库。本通讯报告了MetaboLights作为代谢组学研究的新资源,总结了相关的发展,并概述了它们如何巩固这第三大组学领域的知识管理,仅次于蛋白质组学和基因组学。
Exciting funding initiatives are emerging in Europe and the US for metabolomics data production, storage, dissemination and analysis. This is based on a rich ecosystem of resources around the world, which has been build during the past ten years, including but not limited to resources such as MassBank in Japan and the Human Metabolome Database in Canada. Now, the European Bioinformatics Institute has launched MetaboLights, a database for metabolomics experiments and the associated metadata (http://www.ebi.ac.uk/metabolights). It is the first comprehensive, cross-species, cross-platform metabolomics database maintained by one of the major open access data providers in molecular biology. In October, the European COSMOS consortium will start its work on Metabolomics data standardization, publication and dissemination workflows. The NIH in the US is establishing 6–8 metabolomics services cores as well as a national metabolomics repository. This communication reports about MetaboLights as a new resource for Metabolomics research, summarises the related developments and outlines how they may consolidate the knowledge management in this third large omics field next to proteomics and genomics.
HMDB:人类代谢组数据库。
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