Extracellular Vesicle: An Emerging Mediator of Intercellular Crosstalk in Lung Inflammation and Injury.
Extracellular Vesicle: An Emerging Mediator of Intercellular Crosstalk in Lung Inflammation and Injury.
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细胞外囊泡:肺部炎症与损伤中细胞间相互作用的新兴介质
DOI:
10.3389/fimmu.2018.00924
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发表时间:
2018
影响因子:
7.3
通讯作者:
Jin Y
中科院分区:
文献类型:
--
作者:
Lee H;Abston E;Zhang D;Rai A;Jin Y
Inflammatory lung responses are one of the characterized features in the pathogenesis of many lung diseases, including acute respiratory distress syndrome (ARDS) and chronic obstructive pulmonary disease (COPD). Alveolar macrophages (AMs) and alveolar epithelial cells are the first line of host defense and innate immunity. Due to their central roles in both the initiation and resolution of inflammatory lung responses, AMs constantly communicate with other lung cells, including the alveolar epithelial cells. In the past, emerging evidence suggests that extracellular vesicles play an essential role in cell–cell crosstalk. In this review, we will discuss the recent findings on the intercellular communications between lung epithelial cells and alveolar macrophages, via EV-mediated signal transfer.
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影响因子:
7.3
作者:
Andreu Z;Yáñez-Mó M
通讯作者:
Yáñez-Mó M
影响因子:
16
作者:
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DOI:
10.1016/j.jamcollsurg.2011.12.032
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2012-04
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Pritts, Timothy A.
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4
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7.3
作者:
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