Lumbar spine radiographic features and demographic, clinical, and radiographic knee, hip, and hand osteoarthritis.
Lumbar spine radiographic features and demographic, clinical, and radiographic knee, hip, and hand osteoarthritis.
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DOI：
10.1002/acr.21720
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发表时间：
2012-10
影响因子：
4.7
通讯作者：
Jordan, Joanne M.
中科院分区：
文献类型：
--
作者：
Goode, Adam P.;Marshall, Stephen W.;Renner, Jordan B.;Carey, Timothy S.;Kraus, Virginia B.;Irwin, Debra E.;Stuermer, Til;Jordan, Joanne M.
1)确定腰椎椎间盘间隙狭窄（DSN）、骨赘（OST）和小关节骨关节炎（FOA）个体化影像学特征（IRF）的患病率。2)描述人口统计学、临床和x线摄影的膝关节、髋关节和手骨关节炎（OA）在腰椎IRF中的频率。3)确定腰椎IRF的相关因素。约翰斯顿县OA项目840名参与者的横断面研究（2003-4）。为每个腰椎IRF生成基于样本的患病率估计。腰椎IRF与人口统计学、临床和周围关节OA之间的关系通过logistic回归模型确定。基于样本的患病率估计DSN（57.6%）和FOA（57.9%）相似，但OST（88.1%）更高，在种族和性别之间存在显著差异。手和膝盖OA的频率在IRF中增加，而对髋关节OA没有影响。非裔美国人患FOA的几率较低（校正优势比[aOR]=0.45 (95% CI 0.32, 0.62)），而DSN和OST与种族无关。腰背部症状与DSN相关（aOR=1.37 (95% CI 1.04, 1.80)），但与OST或FOA无关。膝关节OA与OST （aOR=1.62 (95% CI 1.16, 2.27)）和FOA （aOR=1.69 (95% CI 1.15, 2.49)）相关，但与DSN无关。手部OA与FOA相关（aOR=1.67 (95% CI 1.20, 2.28)），但与DSN或OST无关。未发现与髋关节骨性关节炎相关。这些发现强调了单独分析腰椎IRF的重要性，因为它与人口统计学、临床和放射学上的膝关节、髋关节和手部OA的相关性差异很大。
1) To determine the prevalence of lumbar spine individual radiographic features (IRF) of disc space narrowing (DSN), osteophytes (OST) and facet joint osteoarthritis (FOA). 2) To describe the frequencies of demographic, clinic and radiographic knee, hip and hand osteoarthritis (OA) across lumbar spine IRF. 3) To determine factors associated with lumbar spine IRF. A cross-sectional study of 840 participants enrolled in the Johnston County OA Project (2003-4). Sample-based prevalence estimates were generated for each lumbar spine IRF. Associations between lumbar spine IRF and demographic, clinical and peripheral joint OA were determined with logistic regression models. Sample-based prevalence estimates were similar for DSN (57.6%) and FOA (57.9%) but higher for OST (88.1%) with significant differences across race and gender. Hand and knee OA frequencies increased across IRF whereas the effect was absent for hip OA. African Americans had lower odds of FOA (adjusted odds ratio [aOR]=0.45 (95% CI 0.32, 0.62)) while there was no racial association with DSN and OST. Low back symptoms were associated with DSN (aOR=1.37 (95% CI 1.04, 1.80)) but not OST or FOA. Knee OA was associated with OST (aOR=1.62 (95% CI 1.16, 2.27)) and FOA (aOR=1.69 (95% CI 1.15, 2.49)) but not DSN. Hand OA was associated with FOA (aOR=1.67 (95% CI 1.20, 2.28)) but not with DSN or OST. No associations were found with hip OA. These findings underscore the importance of analyzing lumbar spine IRF separately as the associations with demographic, clinic and radiographic knee, hip and hand OA differ widely.
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影响因子：
--
作者：
Dudda, Marcel;Kim, Young-Jo;Zhang, Yuqing;Nevitt, Michael C.;Xu, Ling;Niu, Jingbo;Goggins, Joyce;Doherty, Michael;Felson, David T.
通讯作者：
Felson, David T.
影响因子：
5.3
作者：
Gosvig, Kasper Kjaerulf;Jacobsen, Steffen;Troelsen, Anders
通讯作者：
Troelsen, Anders
影响因子：
3.9
作者：
Allen, Kelli D.;Chen, Jiu-Chiuan;Jordan, Joanne M.
通讯作者：
Jordan, Joanne M.
影响因子：
4.7
作者：
Jordan, JM;Linder, GF;Fryer, JG
通讯作者：
Fryer, JG
影响因子：
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作者：
Davies, HTO;Crombie, IK;Tavakoli, M
通讯作者：
Tavakoli, M