Testing for Drug-Related Infectious Diseases and Determinants among People Who Use Drugs in a Low-Resource Setting: A Respondent-Driven Cross-Sectional Survey.
Testing for Drug-Related Infectious Diseases and Determinants among People Who Use Drugs in a Low-Resource Setting: A Respondent-Driven Cross-Sectional Survey.
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DOI：
10.3390/tropicalmed7090213
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发表时间：
2022-08-29
影响因子：
2.9
通讯作者：
Meyrowitsch DW
中科院分区：
文献类型：
--
作者：
Likindikoki SL;Mmbaga EJ;Mizinduko M;Alexander M;Adams LV;Horsburgh R Jr;Moen K;Leyna G;Lange T;Tersbøl BP;Leshabari M;Meyrowitsch DW
(1)背景资料：关于吸毒者中与毒品有关的传染病检测水平和决定因素的数据缺乏（PWUD）。我们评估了药物相关传染病检测的比例和决定因素，为PWUD的持续干预提供信息。(2)方法：2019年1月至2月在达累斯萨拉姆和坦加进行了一项涉及599名PWUD的横断面研究。通过研究人员使用手持平板电脑进行问卷调查收集数据。Logistic回归模型用于确定药物相关传染病的独立检测决定因素。(3)结果：大多数（98.0%）参与者为男性，平均年龄为36.8（SD = 7.8）岁。75.0%、40.6%、38.6%和8.2%的人报告曾进行过HIV、结核病、性传播感染和病毒性肝炎的检测。艾滋病毒检测的可能性在那些与某人生活在一起的人中更高，（AOR = 2.18，95%CI：1.09-4.68）与无家可归者和认为治疗适当者相比（AOR = 2.18，95% CI：1.05-4.46），但在轻度至中度（AOR = 0.44，95% CI：0.21-0.95）和严重的内化污名（AOR = 0.44，95% CI：0.22-0.94）与那些没有报告内化污名的人相比，在因医疗服务支出而出现经济困难的人群中（AOR = 0.60，95% CI：0.40-0.89）。对治疗适当性的认识（AOR = 2.29，96%CI：1.10-5.06）和严重的已制定的耻辱感（AOR = 1.90，95%CI：1.06-3.42）与结核病检测几率的增加有关。在已婚人群中，（AOR = 2.31，95%CI：1.45-3.72）与单身和轻度（AOR = 2.39，95%CI：1.28-4.53）或重度（AOR = 6.20，95%CI：1.99-23.83）性暴力的受试者与未经历过性暴力的受试者相比。然而，在过去一个月内被还押的人（AOR = 0.64，95%CI：0.43-0.95）与未被还押的人和因医疗保健服务支出而有经济困难的人（AOR = 0.66，95%CI：0.47-0.94）相比，其几率降低。在那些听说过艾滋病毒综合干预包（CHIP）的人中，进行病毒性肝炎检测的可能性增加（AOR = 2.59，95%CI：1.40-4.94）;然而，在那些因医疗保健服务支出而有经济困难的人中，病毒性肝炎检测的可能性降低（AOR = 0.48，95%CI：0.24-0.92）。(4)结论：除HIV外，PWUD接受了有限的药物相关传染病检测。研究结果强调了影响所调查的选定传染病检测的一些因素，这些因素应作为有针对性的干预措施，以改善诊断和治疗。
(1) Background: There is a dearth of data on the levels and determinants of testing for drug-related infectious diseases among people who use drugs (PWUD). We assessed the proportions and determinants of testing for drug-related infectious diseases to inform ongoing interventions for PWUD. (2) Methods: A cross-sectional study involving 599 PWUD was conducted in Dar es Salaam and Tanga between January and February 2019. Data were collected through a researcher-administered questionnaire using handheld tablets. Logistic regression models were used to identify independent testing determinants for drug-related infectious diseases. (3) Results: A majority (98.0%) of participants were males, with a mean age of 36.8 (SD = 7.8) years. 75.0%, 40.6%, 38.6%, and 8.2% reported having ever tested for HIV, tuberculosis (TB), sexually transmitted infections (STIs), and viral hepatitis, respectively. The likelihood of HIV testing was higher among those living with someone (AOR = 2.18, 95% CI: 1.09–4.68) compared with those who were homeless and perceived treatment was appropriate (AOR = 2.18, 95% CI: 1.05–4.46), but was lower among those who experienced mild to moderate (AOR = 0.44, 95% CI: 0.21–0.95) and severe internalized stigma (AOR = 0.44, 95% CI: 0.22–0.94) compared with those reporting no internalized stigma, and among those who experienced financial difficulties resulting from spending on health care services (AOR = 0.60, 95% CI: 0.40–0.89). Perception of treatment appropriateness (AOR = 2.29, 96% CI: 1.10–5.06) and severe enacted stigma (AOR = 1.90, 95% CI: 1.06–3.42) were associated with increased odds of TB testing. The odds of STIs testing increased among those who were married (AOR = 2.31, 95% CI: 1.45–3.72) compared with those who were single and those who had experienced mild (AOR = 2.39, 95% CI: 1.28–4.53) or severe (AOR = 6.20, 95% CI: 1.99–23.83) sexual violence, compared with those who had not experienced sexual violence. However, the odds decreased among those who had been remanded in the past month (AOR = 0.64, 95% CI: 0.43–0.95) compared with those who were not remanded and among those who had financial difficulties resulting from spending on health care services (AOR = 0.66, 95% CI: 0.47–0.94). The likelihood of testing for viral hepatitis testing increased among those who had heard about the comprehensive HIV intervention package (CHIP) (AOR = 2.59, 95% CI: 1.40–4.94); however, it decreased among those who had financial difficulties resulting from spending on health care services (AOR = 0.48, 95% CI: 0.24–0.92). (4) Conclusions: Except for HIV, PWUD had undergone limited testing for drug-related infectious diseases. The study findings highlight some factors influencing testing for the selected infectious diseases investigated, which should be targeted for tailored interventions to improve diagnosis and treatment.
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影响因子：
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作者：
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通讯作者：
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影响因子：
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DOI：
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期刊：
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
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DOI：
10.5588/ijtld.16.0434
发表时间：
2017-04-01
影响因子：
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作者：
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通讯作者：
Garfein, R. S.