An energy model for recognizing the prokaryotic promoters based on molecular structure.
An energy model for recognizing the prokaryotic promoters based on molecular structure.
复制标题
基于分子结构识别原核启动子的能量模型。
DOI:
10.1016/j.ygeno.2019.12.001
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发表时间:
2019-12
期刊:
影响因子:
4.4
通讯作者:
Li Qian-Zhong
中科院分区:
文献类型:
--
作者:
Chen Ying-Li;Guo Dong-Hua;Li Qian-Zhong
Promoter is an important functional elements of DNA sequences, which is in charge of gene transcription initiation. Recognizing promoter have important help for understanding the relative life phenomena. Based on the concept that promoter is mainly determined by its sequence and structure, a novel statistical physics model for predicting promoter inEscherichia coliK-12 is proposed. The total energies of DNA local structure of sequence segments in the three benchmark promoter sequence datasets, the sole prediction parameter, are calculated by using principles from statistical physics and information theory. The better results are obtained. And a web-server PhysMPrePro for predicting promoter is established at http://202.207.14.87:8032/bioinformation/PhysMPrePro/index.asp, so that other scientists can easily get their desired results by our web-server.
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影响因子:
2.9
作者:
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通讯作者:
Ying Huang;Beifang Niu;Ying Gao;L. Fu;Weizhong Li
影响因子:
3
作者:
Mallios RR;Ojcius DM;Ardell DH
通讯作者:
Ardell DH
影响因子:
4.3
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Brewster RC;Jones DL;Phillips R
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Phillips R
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3
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