Mammalian pheromones.
Mammalian pheromones.
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哺乳动物信息素。
DOI:
10.1146/annurev-physiol-021113-170334
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发表时间:
2014
影响因子:
18.2
通讯作者:
Liberles SD
中科院分区:
文献类型:
--
作者:
Liberles SD
Mammalian pheromones control a myriad of innate social behaviors and acutely regulate hormone levels. Responses to pheromones are highly robust, reproducible, and stereotyped and likely involve developmentally predetermined neural circuits. Here, I review several facets of pheromone transduction in mammals, including (a) chemosensory receptors and signaling components of the main olfactory epithelium and vomeronasal organ involved in pheromone detection; (b) pheromone-activated neural circuits subject to sex-specific and state-dependent modulation; and (c) the striking chemical diversity of mammalian pheromones, which range from small, volatile molecules and sulfated steroids to large families of proteins. Finally, I review (d ) molecular mechanisms underlying various behavioral and endocrine responses, including modulation of puberty and estrous; control of reproduction, aggression, suckling, and parental behaviors; individual recognition; and distinguishing of own species from predators, competitors, and prey. Deconstruction of pheromone transduction mechanisms provides a critical foundation for understanding how odor response pathways generate instinctive behaviors.
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影响因子:
1.7
作者:
Dorries, KM;AdkinsRegan, E;Halpern, BP
通讯作者:
Halpern, BP
影响因子:
8.2
作者:
Apfelbach, R;Blanchard, CD;McGregor, IS
通讯作者:
McGregor, IS
DOI:
10.1073/pnas.1214249110
发表时间:
2013-03-19
影响因子:
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作者:
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通讯作者:
Broillet, Marie-Christine
影响因子:
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通讯作者:
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通讯作者:
Stowers, Lisa