Temporally and spatially distinct theta oscillations dissociate a language-specific from a domain-general processing mechanism across the age trajectory.
Temporally and spatially distinct theta oscillations dissociate a language-specific from a domain-general processing mechanism across the age trajectory.
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DOI：
10.1038/s41598-017-11632-z
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发表时间：
2017-09-11
影响因子：
4.6
通讯作者：
Friederici AD
中科院分区：
文献类型：
--
作者：
Beese C;Meyer L;Vassileiou B;Friederici AD
神经振荡的认知功能仍然存在很大争议，因为不同的功能与相同的频率范围有关。例如，Theta波段振荡被认为是语言理解和领域一般认知能力的基础。在这里，我们表明，老化的大脑可以提供一个答案，以开放的问题，它是否是一个和相同的θ振荡的基础上，这些功能，从而解决了一个长期存在的悖论。虽然更好的认知功能是由休息时大脑中的低θ功率预测的，但休息状态（RS）θ功率随着年龄的增长而下降，但句子理解在老年时会恶化。我们解决这个悖论表明，句子理解下降，由于在域一般的大脑网络中的RS θ功率的变化，以支持成功的句子理解，而低RS θ功率在左半球背额叶语言网络预测完整的句子理解。还发现两个RS θ网络相对于其独立的内部耦合在功能上解耦。因此，时间和空间上不同的RS theta振荡都将特定语言与通用领域的处理机制分离开来。
The cognitive functionality of neural oscillations is still highly debated, as different functions have been associated with identical frequency ranges. Theta band oscillations, for instance, were proposed to underlie both language comprehension and domain-general cognitive abilities. Here we show that the ageing brain can provide an answer to the open question whether it is one and the same theta oscillation underlying those functions, thereby resolving a long-standing paradox. While better cognitive functioning is predicted by low theta power in the brain at rest, resting state (RS) theta power declines with age, but sentence comprehension deteriorates in old age. We resolve this paradox showing that sentence comprehension declines due to changes in RS theta power within domain-general brain networks known to support successful sentence comprehension, while low RS theta power within the left-hemispheric dorso-frontal language network predicts intact sentence comprehension. The two RS theta networks were also found to functionally decouple relative to their independent internal coupling. Thus, both temporally and spatially distinct RS theta oscillations dissociate a language-specific from a domain-general processing mechanism.
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DOI：
10.1523/jneurosci.0828-11.2011
发表时间：
2011-07-27
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Hsieh LT;Ekstrom AD;Ranganath C
通讯作者：
Ranganath C
影响因子：
3.7
作者：
Grandy, Thomas H.;Werkle-Bergner, Markus;Lindenberger, Ulman
通讯作者：
Lindenberger, Ulman
DOI：
10.1037/0278-7393.27.6.1411
发表时间：
2001-11-01
影响因子：
2.6
作者：
Gordon, PC;Hendrick, R;Johnson, M
通讯作者：
Johnson, M
影响因子：
3.7
作者：
Caplan, David;DeDe, Gayle;Tripodis, Yorghos
通讯作者：
Tripodis, Yorghos
影响因子：
3.7
作者：
Finnigan, Simon;Robertson, Ian H.
通讯作者：
Robertson, Ian H.