The Role of Transposable Elements in Speciation.

The Role of Transposable Elements in Speciation.
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DOI:
10.3390/genes9050254
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发表时间:
2018-05-15
期刊:
影响因子:
3.5
通讯作者:
Matute DR
Matute DR
中科院分区:
生物学3区
文献类型:
--
作者:
Serrato-Capuchina A;Matute DR

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了解有助于物种间和物种内遗传多样性的表型和分子机制是研究物种进化的基础。特别是,识别导致新生物种之间基因流减少甚至停止的种间差异是物种形成遗传学研究的主要目标之一。转座元件 (TE) 是能够在基因组内移动的 DNA 序列。 TE 在真核生物基因组中普遍存在,并已被证明可以改变调控网络、基因表达,并通过转座重新排列基因组。然而,还没有系统性的工作评估 TE 在物种形成中的作用。我们整理了 TE 作为多种类群生殖隔离的潜在原因的证据。我们发现,TE 通常与杂种缺陷相关,这些缺陷可能会阻碍物种之间的融合,但 TE 在与合子后隔离不同的其他基因流动障碍中的作用仍然相对未知。最后,我们列出了一系列指南和研究途径,以阐明 TE 对新物种起源的影响。
Understanding the phenotypic and molecular mechanisms that contribute to genetic diversity between and within species is fundamental in studying the evolution of species. In particular, identifying the interspecific differences that lead to the reduction or even cessation of gene flow between nascent species is one of the main goals of speciation genetic research. Transposable elements (TEs) are DNA sequences with the ability to move within genomes. TEs are ubiquitous throughout eukaryotic genomes and have been shown to alter regulatory networks, gene expression, and to rearrange genomes as a result of their transposition. However, no systematic effort has evaluated the role of TEs in speciation. We compiled the evidence for TEs as potential causes of reproductive isolation across a diversity of taxa. We find that TEs are often associated with hybrid defects that might preclude the fusion between species, but that the involvement of TEs in other barriers to gene flow different from postzygotic isolation is still relatively unknown. Finally, we list a series of guides and research avenues to disentangle the effects of TEs on the origin of new species.
DOI: 10.1038/hdy.1994.185
发表时间: 1994-10-01
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