Associations of sedentary behavior, sedentary bouts and breaks in sedentary time with cardiometabolic risk in children with a family history of obesity.
Associations of sedentary behavior, sedentary bouts and breaks in sedentary time with cardiometabolic risk in children with a family history of obesity.
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DOI：
10.1371/journal.pone.0079143
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发表时间：
2013
期刊：
影响因子：
3.7
通讯作者：
QUALITY cohort research group
中科院分区：
文献类型：
--
作者：
Saunders TJ;Tremblay MS;Mathieu MÈ;Henderson M;O'Loughlin J;Tremblay A;Chaput JP;QUALITY cohort research group
尽管成人报告表明，久坐时间的休息与心脏代谢风险降低有关，但这些发现尚未在儿童中得到重复。目的：在一组有肥胖家族史的 8-11 岁加拿大儿童中，调查客观测量的久坐行为、久坐次数或久坐时间的中断是否与心脏代谢风险独立相关。 2005 年至 2008 年，我们收集了居住在加拿大魁北克省的 286 名男孩和 236 名女孩的数据，他们的亲生父母中至少有一位患有肥胖症（QUALITY 队列），并于 2013 年进行了分析。使用加速度测量法测量了 7 天的久坐行为、轻度和中度至剧烈的体力活动。自我报告过去 7 天的闲暇时间电脑/视频游戏使用情况和电视观看情况。结果包括腰围、体重指数 Z 评分、空腹胰岛素、空腹血糖、甘油三酯、HDL 胆固醇、C 反应蛋白和连续心脏代谢风险评分。调整混杂因素后，两性中，久坐时间的中断和持续 1-4 分钟久坐的次数与心脏代谢风险评分降低和 BMI Z 评分降低相关（所有 p<0.05）。持续 5-9 分钟的久坐次数仅与女孩的腰围呈负相关，而持续 10-14 分钟的久坐次数与女孩的空腹血糖呈正相关，与男孩的 BMI Z 分数呈正相关（均 p<0.05）。休闲时间使用电脑/视频游戏与男孩的心脏代谢风险评分和腰围增加相关，而看电视与女孩的心脏代谢风险、腰围和 BMI Z 分数增加相关（所有 p<0.05）。这些结果表明，久坐时间的频繁中断与良好的心脏代谢风险状况相关，并强调了有肥胖家族史的儿童中屏幕时间与心脏代谢风险之间的有害关系。
Although reports in adults suggest that breaks in sedentary time are associated with reduced cardiometabolic risk, these findings have yet to be replicated in children. To investigate whether objectively measured sedentary behavior, sedentary bouts or breaks in sedentary time are independently associated with cardiometabolic risk in a cohort of Canadian children aged 8–11 years with a family history of obesity. Data from 286 boys and 236 girls living in Quebec, Canada, with at least one biological parent with obesity (QUALITY cohort) were collected from 2005–2008, and analyzed in 2013. Sedentary behavior, light and moderate-to-vigorous physical activity were measured over 7 days using accelerometry. Leisure time computer/video game use and TV viewing over the past 7 days were self-reported. Outcomes included waist circumference, body mass index Z-score, fasting insulin, fasting glucose, triglycerides, HDL-cholesterol, C-reactive protein and a continuous cardiometabolic risk score. After adjustment for confounders, breaks in sedentary time and the number of sedentary bouts lasting 1–4 minutes were associated with reduced cardiometabolic risk score and lower BMI Z-score in both sexes (all p<0.05). The number of sedentary bouts lasting 5–9 minutes was negatively associated with waist circumference in girls only, while the number of bouts lasting 10–14 minutes was positively associated with fasting glucose in girls, and with BMI Z-score in boys (all p<0.05). Leisure time computer/video game use was associated with increased cardiometabolic risk score and waist circumference in boys, while TV viewing was associated with increased cardiometabolic risk, waist circumference, and BMI Z-score in girls (all p<0.05). These results suggest that frequent interruptions in sedentary time are associated with a favourable cardiometabolic risk profile and highlight the deleterious relationship between screen time and cardiometabolic risk among children with a family history of obesity.
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影响因子：
120.7
作者：
Ekelund, Ulf;Luan, Jian'an;Sherar, Lauren B.;Esliger, Dale W.;Griew, Pippa;Cooper, Ashley
通讯作者：
Cooper, Ashley
影响因子：
16.2
作者：
Dunstan DW;Kingwell BA;Larsen R;Healy GN;Cerin E;Hamilton MT;Shaw JE;Bertovic DA;Zimmet PZ;Salmon J;Owen N
通讯作者：
Owen N
影响因子：
7.7
作者：
Hamilton, Marc T.;Hamilton, Deborah G.;Zderic, Theodore W.
通讯作者：
Zderic, Theodore W.
影响因子：
8
作者：
Boney, CM;Verma, A;Vohr, BR
通讯作者：
Vohr, BR
影响因子：
4.1
作者：
Atkin, Andrew J.;Ekelund, Ulf;Brage, Soren
通讯作者：
Brage, Soren