Human seasonal influenza under COVID-19 and the potential consequences of influenza lineage elimination.
Human seasonal influenza under COVID-19 and the potential consequences of influenza lineage elimination.
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DOI：
10.1038/s41467-022-29402-5
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发表时间：
2022-03-31
影响因子：
16.6
通讯作者：
Barr IG
中科院分区：
文献类型：
--
作者：
Dhanasekaran V;Sullivan S;Edwards KM;Xie R;Khvorov A;Valkenburg SA;Cowling BJ;Barr IG
每年季节性流感的流行造成数十万人死亡，高发病率和巨大的经济损失。然而，自2019冠状病毒病大流行爆发以来，公共卫生措施和旅行限制严重抑制了全球流感传播。值得注意的是，自2020年4月以来，B型/山形流感谱系尚未被最终检测到，此后，A（H3N2）、A（H1N1）和B/维多利亚病毒的遗传多样性大大减少。旅行限制在很大程度上限制了A（H3N2）在南亚和东南亚的区域性暴发，B/Victoria在中国的暴发，以及A（H1N1）在西非的暴发。季节性流感传播谱系在全球范围内继续消亡，但在这些选定的热点地区除外，这可能会为未来的流行病播下种子。人口免疫力下降和散发病例发现将进一步挑战流感疫苗毒株选择和流行病控制。我们提出了季节性流感潜在的短期和长期演化动态的观点，并讨论了随着全球旅行逐渐恢复到大流行前水平的潜在后果和缓解战略。COVID-19控制措施抑制了包括流感在内的其他感染的传播。在此，作者分析了世卫组织全球流感序列和病例报告数据，并描述了COVID-19大流行期间流感谱系的系统发育和地理分布变化。
Annual epidemics of seasonal influenza cause hundreds of thousands of deaths, high levels of morbidity, and substantial economic loss. Yet, global influenza circulation has been heavily suppressed by public health measures and travel restrictions since the onset of the COVID-19 pandemic. Notably, the influenza B/Yamagata lineage has not been conclusively detected since April 2020, and A(H3N2), A(H1N1), and B/Victoria viruses have since circulated with considerably less genetic diversity. Travel restrictions have largely confined regional outbreaks of A(H3N2) to South and Southeast Asia, B/Victoria to China, and A(H1N1) to West Africa. Seasonal influenza transmission lineages continue to perish globally, except in these select hotspots, which will likely seed future epidemics. Waning population immunity and sporadic case detection will further challenge influenza vaccine strain selection and epidemic control. We offer a perspective on the potential short- and long-term evolutionary dynamics of seasonal influenza and discuss potential consequences and mitigation strategies as global travel gradually returns to pre-pandemic levels. COVID-19 control measures have suppressed circulation of other infections including influenza. Here, the authors analyse WHO global influenza sequence and case report data and describe changes in the phylogenetic and geographic distribution of influenza lineages during the COVID-19 pandemic.
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影响因子：
16.6
作者：
Huang QS;Wood T;Jelley L;Jennings T;Jefferies S;Daniells K;Nesdale A;Dowell T;Turner N;Campbell-Stokes P;Balm M;Dobinson HC;Grant CC;James S;Aminisani N;Ralston J;Gunn W;Bocacao J;Danielewicz J;Moncrieff T;McNeill A;Lopez L;Waite B;Kiedrzynski T;Schrader H;Gray R;Cook K;Currin D;Engelbrecht C;Tapurau W;Emmerton L;Martin M;Baker MG;Taylor S;Trenholme A;Wong C;Lawrence S;McArthur C;Stanley A;Roberts S;Rahnama F;Bennett J;Mansell C;Dilcher M;Werno A;Grant J;van der Linden A;Youngblood B;Thomas PG;NPIsImpactOnFlu Consortium;Webby RJ
通讯作者：
Webby RJ
影响因子：
10.7
作者：
Barrat-Charlaix P;Huddleston J;Bedford T;Neher RA
通讯作者：
Neher RA
影响因子：
19
作者：
Kissling, E.;Nunes, B.;Moren, A.
通讯作者：
Moren, A.
DOI：
10.1016/j.lana.2021.100015
发表时间：
2021-09
期刊：
Lancet regional health. Americas
影响因子：
--
作者：
Groves HE;Piché-Renaud PP;Peci A;Farrar DS;Buckrell S;Bancej C;Sevenhuysen C;Campigotto A;Gubbay JB;Morris SK
通讯作者：
Morris SK
影响因子：
6.7
作者：
Geoghegan JL;Saavedra AF;Duchêne S;Sullivan S;Barr I;Holmes EC
通讯作者：
Holmes EC