Social economic decision-making across the lifespan: An fMRI investigation.
Social economic decision-making across the lifespan: An fMRI investigation.
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DOI：
10.1016/j.neuropsychologia.2012.02.026
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发表时间：
2012-06
期刊：
影响因子：
2.6
通讯作者：
Sanfey AG
中科院分区：
文献类型：
--
作者：
Harlé KM;Sanfey AG
最近的神经经济学研究表明，社会经济决策可能是最好的理解为一个双系统的过程，整合审议和情感子系统的影响。然而，大多数研究都集中在年轻人身上，目前还不清楚我们目前的模型是否适用于健康的老龄化。为了解决这个问题，我们调查了18名年轻人和20名老年健康成年人的简单经济决策的行为和神经基础。参与者在最后通牒游戏中做出决定，包括接受或拒绝人类和非人类（计算机）合作伙伴的金钱提议，同时进行功能性磁共振成像（fMRI）。合伙人的提议包括在两个玩家之间平分一笔钱，从1美元到5美元不等（从10美元的底池开始）。相对于年轻人，老年参与者期望更公平的报价，并拒绝适度不公平的报价（3美元）在更大程度上。成像结果显示，相对于年轻的参与者，老年人在接受不公平的报价（1 - 3美元）时，左背外侧前额叶皮层（DLPFC）的激活程度更高。年龄组调节左DLPFC激活和接受率的不公平提供之间的关系。相比之下，老年人在不公平的条件下，双侧前额叶的激活程度较低。当参与者收到公平的（5美元）报价时，没有观察到年龄组差异。这些研究结果表明，健康的老龄化可能与更强的依赖于计算领域subserving目标维护和规则转换（DLPFC）在互动的经济决策。与一个有据可查的“积极性效应”相一致，面对社会规范的违反，老年也可能减少涉及情绪处理和整合（前额叶）的区域的招聘。
Recent research in neuroeconomics suggests that social economic decision-making may be best understood as a dual-systems process, integrating the influence of deliberative and affective subsystems. However, most of this research has focused on young adults and it remains unclear whether our current models extend to healthy aging. To address this question, we investigated the behavioral and neural basis of simple economic decisions in 18 young and 20 older healthy adults. Participants made decisions which involved accepting or rejecting monetary offers from human and non-human (computer) partners in an Ultimatum Game, while undergoing functional magnetic resonance imaging (fMRI). The partners’ proposals involved splitting an amount of money between the two players, and ranged from $1 to $5 (from a $10 pot). Relative to young adults, older participants expected more equitable offers and rejected moderately unfair offers ($3) to a larger extent. Imaging results revealed that, relative to young participants, older adults had higher activations in the left dorsolateral prefrontal cortex (DLPFC) when receiving unfair offers ($1–$3). Age group moderated the relationship between left DLPFC activation and acceptance rates of unfair offers. In contrast, older adults showed lower activation of bilateral anterior insula in response to unfair offers. No age group difference was observed when participants received fair ($5) offers. These findings suggest that healthy aging may be associated with a stronger reliance on computational areas subserving goal maintenance and rule shifting (DLPFC) during interactive economic decision-making. Consistent with a well-documented “positivity effect”, older age may also decrease recruitment of areas involved in emotion processing and integration (anterior insula) in the face of social norm violation.
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DOI：
10.1073/pnas.96.14.8301
发表时间：
1999-07-06
影响因子：
11.1
作者：
Garavan, H;Ross, TJ;Stein, EA
通讯作者：
Stein, EA
影响因子：
4.2
作者：
Harle, Katia M.;Sanfey, Alan G.
通讯作者：
Sanfey, Alan G.
影响因子：
3.2
作者：
Denson, Thomas F.;Pedersen, William C.;Nandy, Anirvan S.
通讯作者：
Nandy, Anirvan S.
影响因子：
3.7
作者：
CARSTENSEN, LL
通讯作者：
CARSTENSEN, LL
影响因子：
2.2
作者：
GUTH, W;SCHMITTBERGER, R;SCHWARZE, B
通讯作者：
SCHWARZE, B