Population attributable risk of breast cancer in white women associated with immediately modifiable risk factors.
Population attributable risk of breast cancer in white women associated with immediately modifiable risk factors.
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与立即改变的危险因素相关的白人妇女乳腺癌风险。
DOI：
10.1186/1471-2407-6-170
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发表时间：
2006-06-27
期刊：
影响因子：
3.8
通讯作者：
Glaser, Sally L.
中科院分区：
文献类型：
--
作者：
Clarke, Christina A.;Purdie, David M.;Glaser, Sally L.
雌激素/孕酮替代疗法（EPRT）、饮酒、体力活动和母乳喂养时间与其他与乳腺癌相关的因素不同，这些因素可由个体立即改变，因此代表了未来乳腺癌预防工作的有吸引力的目标。为了证明这些努力的合理性，考虑到行为患病率、风险估计和基线发病率的人群差异，量化人群水平对乳腺癌的潜在影响至关重要。对于这四个因素中的每一个，我们使用基于人群的调查（2001年）和癌症登记数据（1998 - 2002年）计算了41个年龄在40 - 79岁的白色、非西班牙裔加州妇女亚群的人群归因风险因子（PAR），以及文献中的相对风险（RR）估计范围。使用单一RR估计，激素使用的亚群PAR范围为2.5%至5.6%，近期每日饮酒≥ 2次的亚群PAR范围为0.0%至6.1%，缺乏体力活动的亚群PAR范围为4.6%至11.0%。使用一系列RR估计值，使用EPRT的PAR为2 - 11%，饮酒为1 - 20%，缺乏体力活动为2 - 15%。母乳喂养的亚群数据不可用，但使用已发表的RR估计值，终生母乳喂养≥ 31个月的PAR范围为2%至11%。因此，在加州每年诊断出的13,019例乳腺癌中，多达1,432例可归因于EPRT的使用，2,604例可归因于饮酒，1,953例可归因于身体活动不足，1,432例可归因于从未母乳喂养。相对可行的生活方式的改变，停止使用EPRT，减少饮酒，增加体力活动，延长母乳喂养时间可以大大降低人群乳腺癌的发病率。
Estrogen/progestin replacement therapy (EPRT), alcohol consumption, physical activity, and breast-feeding duration differ from other factors associated with breast cancer in being immediately modifiable by the individual, thereby representing attractive targets for future breast cancer prevention efforts. To justify such efforts, it is vital to quantify the potential population-level impacts on breast cancer considering population variations in behavior prevalence, risk estimate, and baseline incidence. For each of these four factors, we calculated population attributable risk percents (PARs) using population-based survey (2001) and cancer registry data (1998–2002) for 41 subpopulations of white, non-Hispanic California women aged 40–79 years, and ranges of relative risk (RR) estimates from the literature. Using a single RR estimate, subpopulation PARs ranged from 2.5% to 5.6% for hormone use, from 0.0% to 6.1% for recent consumption of >= 2 alcoholic drinks daily, and 4.6% to 11.0% for physical inactivity. Using a range of RR estimates, PARs were 2–11% for EPRT use, 1–20% for alcohol consumption and 2–15% for physical inactivity. Subpopulation data were unavailable for breastfeeding, but PARs using published RR estimates ranged from 2% to 11% for lifetime breastfeeding >= 31 months. Thus, of 13,019 breast cancers diagnosed annually in California, as many as 1,432 attributable to EPRT use, 2,604 attributable to alcohol consumption, 1,953 attributable to physical inactivity, and 1,432 attributable to never breastfeeding might be avoidable. The relatively feasible lifestyle changes of discontinuing EPRT use, reducing alcohol consumption, increasing physical activity, and lengthening breastfeeding duration could lower population breast cancer incidence substantially.
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影响因子：
8.8
作者：
Beral, V;Hamajima, N;Hirose, K;Rohan, T;Calle, EE;Heath, CW;Coates, RJ;Liff, JM;Talamini, R;Chantarakul, N;Koetsawang, S;Rachawat, D;Morabia, A;Schuman, L;Stewart, W;Szklo, M;Bain, C;Schofield, F;Siskind, V;Band, P;Coldman, AJ;Gallagher, RP;Hislop, TG;Yang, P;Kolonel, LM;Nomura, AMY;Hu, J;Johnson, KC;Mao, Y;De Sanjose, S;Lee, N;Marchbanks, P;Ory, HW;Peterson, HB;Wilson, HG;Wingo, PA;Ebeling, K;Kunde, D;Nishan, P;Hopper, JL;Colditz, G;Gajalakshmi, V;Martin, N;Pardthaisong, T;Solpisornkosol, S;Theetranont, C;Boosiri, B;Chutivongse, S;Jimakorn, P;Virutamasen, P;Wongsrichanalai, C;Ewertz, M;Adami, HO;Bergkvist, L;Magnusson, C;Persson, I;Chang-Claude, J;Paul, C;Skegg, DCG;Spears, GFS;Boyle, P;Evstifeeva, T;Daling, JR;Hutchinson, WB;Malone, K;Noonan, EA;Stanford, JL;Thomas, DB;Weiss, NS;White, E;Andrieu, N;Brêmond, A;Clavel, F;Gairard, B;Lansac, J;Piana, L;Renaud, R;Izquierdo, A;Viladiu, P;Cuevas, HR;Ontiveros, P;Palet, A;Salazar, SB;Arsitizabal, N;Cuadros, A;Tryggvadottir, L;Tulinius, H;Bachelot, A;Lê, MG;Peto, J;Franceschi, S;Lubin, F;Modan, B;Ron, E;Wax, Y;Friedman, GD;Hiatt, RA;Levi, F;Bishop, T;Kosmelj, K;Primic-Zakelj, M;Ravnihar, B;Stare, J;Beeson, WL;Fraser, G;Bulbrook, RD;Cuzick, J;Duffy, SW;Fentiman, IS;Hayward, JL;Wang, DY;McMichael, AJ;McPherson, K;Hanson, RL;Leske, MC;Mahoney, MC;Nasca, PC;Varma, AO;Weinstein, AL;Moller, TR;Olsson, H;Ranstam, J;Goldbohm, RA;van den Brandt, PA;Apelo, RA;Baens, J;de la Cruz, JR;Javier, B;Lacaya, LB;Ngelangel, CA;La Vecchia, C;Negri, E;Marubini, E;Ferraroni, M;Gerber, M;Richardson, S;Segala, C;Gatei, D;Kenya, P;Kungu, A;Mati, JG;Brinton, LA;Hoover, R;Schairer, C;Spirtas, R;Lee, HP;Rookus, MA;van Leeuwen, FE;Schoenberg, JA;McCredie, M;Gammon, MD;Clarke, EA;Jones, L;Neil, A;Vessey, M;Yeates, D;Appleby, P;Banks, E;Bull, D;Crossley, B;Goodill, A;Green, J;Hermon, C;Key, T;Langston, N;Lewis, C;Reeves, G;Collins, R;Doll, R;Peto, R;Mabuchi, K;Preston, D;Hannaford, P;Kay, C;Rosero-Bixby, L;Gao, YT;Jin, F;Yuan, JM;Wei, HY;Yun, T;Zhiheng, C;Berry, G;Cooper Booth, J;Jelihovsky, T;MacLennan, R;Shearman, R;Wang, QS;Baines, CJ;Miller, AB;Wall, C;Lund, E;Stalsberg, H;Shu, XO;Zheng, W;Katsouyanni, K;Trichopoulou, A;Trichopoulos, D;Dabancens, A;Martinez, L;Molina, R;Salas, O;Alexander, XE;Anderson, K;Folsom, AR;Hulka, BS;Bernstein, L;Enger, S;Haile, RW;Paganini-Hill, A;Pike, MC;Ross, RK;Ursin, G;Yu, MC;Longnecker, MP;Newcomb, P;Bergkvist, L;Kalache, A;Farley, TMM;Holck, S;Meirik, O
通讯作者：
Meirik, O
影响因子：
6.2
作者：
Bernstein, Leslie;Teal, Cayla R.;Wilson, Jerome
通讯作者：
Wilson, Jerome
影响因子：
8.4
作者：
Coombes, NJ;Taylor, R;Boyages, J
通讯作者：
Boyages, J
DOI：
10.1093/jnci/87.22.1681
发表时间：
1995-11-15
期刊：
JOURNAL OF THE NATIONAL CANCER INSTITUTE
影响因子：
--
作者：
MADIGAN, MP;ZIEGLER, RG;HOOVER, RN
通讯作者：
HOOVER, RN
影响因子：
2.3
作者：
Tseng, M;Weinberg, CR;Longnecker, MP
通讯作者：
Longnecker, MP