Depression pandemic and cardiovascular risk in the COVID-19 era and long COVID syndrome: Gender makes a difference.

Depression pandemic and cardiovascular risk in the COVID-19 era and long COVID syndrome: Gender makes a difference.
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DOI:
10.1016/j.tcm.2021.09.009
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发表时间:
2022-01
影响因子:
9.3
通讯作者:
Mattioli AV
Mattioli AV
中科院分区:
医学2区
文献类型:
--
作者:
Bucciarelli V;Nasi M;Bianco F;Seferovic J;Ivkovic V;Gallina S;Mattioli AV

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持续的COVID-19大流行凸显了心血管疾病(CVD)、COVID-19相关炎症状态和抑郁症之间的显著相互作用。心血管(CV)损伤是导致COVID-19死亡的重要原因,而COVID-19社会限制成为CVD以及各种心理健康问题(特别是抑郁症)的不可忽视的风险因素。炎症似乎是这两种疾病之间的共同条件。性别是CVD和抑郁症以及COVID-19短期和长期结局的潜在调整因素,特别是在涉及长期COVID并发症的病例中。新研究的结果表明,COVID-19大流行以不同的方式影响男性和女性人群。女性的短期并发症似乎不太严重,但长期COVID并发症更严重,包括抑郁症、体力活动减少和生活习惯恶化,所有这些都可能影响CV风险。在这里,我们总结了关于COVID-19、抑郁症和女性CV风险之间相互作用的知识现状。
The ongoing COVID-19 pandemic highlighted a significant interplay between cardiovascular disease (CVD), COVID-19 related inflammatory status, and depression. Cardiovascular (CV) injury is responsible for a substantial percentage of COVID-19 deaths while COVID-19 social restrictions emerged as a non-negligible risk factor for CVD as well as a variety of mental health issues, and in particular, depression. Inflammation seems to be a shared condition between these two disorders. Gender represents a potential modifying factor both in CVD and depression, as well as in COVID-19 short- and long-term outcomes, particularly in cases involving long-term COVID complications. Results from emerging studies indicate that COVID-19 pandemic affected male and female populations in different ways. Women seem to experience less severe short-term complications but suffer worse long-term COVID complications, including depression, reduced physical activity, and deteriorating lifestyle habits, all of which may impact CV risk. Here, we summarize the current state of knowledge about the interplay between COVID-19, depression, and CV risk in women.
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