Prevalence of HTLV-III/LAV in household contacts of patients with confirmed AIDS and controls in Kinshasa, Zaire.
Prevalence of HTLV-III/LAV in household contacts of patients with confirmed AIDS and controls in Kinshasa, Zaire.
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扎伊尔金沙萨确诊艾滋病患者和对照患者的家庭接触者中 HTLV-III/LAV 的患病率。
DOI：
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
James Curran
中科院分区：
文献类型：
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作者：
JonathanM. Mann;T. C. Quinn;H. Francis;N. Nzilambi;N. Bosenge;Kapita Bila;Joseph B. McCormick;K. Ruti;P. Asila;James Curran
46例确诊为获得性免疫缺陷综合征（艾滋病）患者和43例来自扎伊尔金沙萨的人类T细胞嗜淋巴细胞病毒III型/淋巴结病相关病毒（HTLV-III/LAV）血清阴性对照的家庭成员进行了鉴定，并寻求血清学检测HTLV-III/LAV感染的证据。204名病例家庭成员中有20名（9.8%）和155名对照家庭成员中有3名（1.9%）为HTLV-III/LAV血清阳性（相对危险度= 5.1; 95%置信区间，1.7至15.2）。18例艾滋病患者配偶中有11例（61.1%）HTLV-III/LAV血清阳性，而27例对照配偶中有1例（3.7%）阳性（相对危险度= 16.5; 95%可信区间为3.7 ~ 75.0）。除配偶外，HTLV-III/LAV血清阳性率在病例和对照家庭之间没有显著差异。此外，对于非配偶的病例家庭中的成年人，HTLV-III/LAV血清阳性的人数与根据性别和年龄特异性HTLV-III/LAV血清阳性率预测的人数相同。这些来自扎伊尔的数据证实了美国和欧洲对受感染的血友病患者和艾滋病儿科患者的家庭接触的研究结果。
Household members of 46 patients with confirmed acquired immunodeficiency syndrome (AIDS) and 43 human T-cell lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV)-seronegative controls from Kinshasa, Zaire, were identified and sought for serologic testing for evidence of HTLV-III/LAV infection. Twenty (9.8%) of 204 case-household members and three (1.9%) of 155 control-household members were HTLV-III/LAV seropositive (relative risk = 5.1; 95% confidence interval, 1.7 to 15.2). Eleven (61.1%) of 18 spouses of patients with AIDS were HTLV-III/LAV seropositive, compared with one (3.7%) of 27 control spouses (relative risk = 16.5; 95% confidence interval, 3.7 to 75.0). Except for spouses, the rate of HTLV-III/LAV seropositivity did not differ significantly between case and control households. Furthermore, for adults in case households who were not spouses, the number seropositive for HTLV-III/LAV was identical to that predicted from sex- and age-specific HTLV-III/LAV seroprevalence rates. These data from Zaire confirm the results of US and European studies of household contacts of infected hemophiliacs and pediatric patients with AIDS.
患有艾滋病相关综合症的人和有艾滋病风险的健康男同性恋者唾液中的 HTLV-III。
DOI：
10.1126/science.6093247
发表时间：
1984
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Groopman,JE;Salahuddin,SZ;Sarngadharan,MG;Markham,PD;Gonda,M;Sliski,A;Gallo,RC
通讯作者：
Gallo,RC
血友病患者妻子体内的人类 T 淋巴细胞病毒 III 型抗体。
影响因子：
39.2
作者：
Kreiss,JK;Kitchen,LW;Prince,HE;Kasper,CK;Essex,M
通讯作者：
Essex,M
患有获得性免疫缺陷综合症的男性女性性伴侣的免疫缺陷。
DOI：
10.1056/nejm198305193082001
发表时间：
1983
期刊：
The New England journal of medicine
影响因子：
--
作者：
Harris,C;Small,CB;Klein,RS;Friedland,GH;Moll,B;Emeson,EE;Spigland,I;Steigbigel,NH
通讯作者：
Steigbigel,NH