Optimization of the Thin Waveguide for Double-Parabolic-Reflectors Ultrasonic Transducers (DPLUS) for Thermal Ablation

Optimization of the Thin Waveguide for Double-Parabolic-Reflectors Ultrasonic Transducers (DPLUS) for Thermal Ablation
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用于热烧蚀的双抛物面反射器超声波换能器 (DPLUS) 薄波导的优化

DOI:
10.1109/tbme.2022.3197213
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发表时间:
2023
影响因子:
4.6
通讯作者:
Morita Takeshi
Morita Takeshi
中科院分区:
工程技术2区
文献类型:
--
作者:
Chen Kang;Irie Takasuke;Iijima Takashi;Miyake Susumu;Morita Takeshi

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组织间超声和腔内超声已经被开发和研究用于微创治疗(MIT)。然而,声学输出受到小尺寸PZT的限制。因此,我们研究了声波波导(AW)的施加器,使使用一个大尺寸的PZT,我们的目的是推进AW施加器对热消融application.MethodsDouble抛物面反射器波导超声换能器(DPLUS)介绍了它有两个抛物面反射器,用于提高声输出。对DPLUS薄波导进行了理论建模,优化结果表明,可以找到最佳的(薄波导半径/波长),最佳值取决于薄波导中的可激励振动幅度。最后,在0.6mm半径下,选取局部最优值= 0.2392,得到最优频率为2.2MHz,并在1.0282MHz和2.2579MHz两个工作频率下进行了实验验证。鸡胸肉组织的温升曲线与实验结果吻合较好,证明了模型的有效性。在2.2579MHz、5s的连续激励下,消融区直径为1.03± 0.12mm。结论:DPLUS的研制使AW施源器向热消融应用的方向发展,为认识AW施源器作为一种热消融技术提供了依据。
ObjectiveInterstitial and intracavitary ultra- sound applicators had been developed and studied for minimally invasive treatments (MIT). However, the acoustic outputs are limited by the small-size PZT. We therefore studied the acoustic waveguide (AW) applicator which enables the use of a large-size PZT, and we aimed to advance AW applicators towards thermal ablation applications.MethodsDouble parabolic reflectors wave-guided ultrasonic transducer (DPLUS) was introduced which has two parabolic reflectors for enhancing the acoustic output. Theoretical modeling was conducted for optimizing the DPLUS thin waveguide.ResultsModeling results showed that optimal(thin waveguide radius/wavelength) can be found and the optimaldepends on the excitable vibration amplitude in the thin waveguide. A local optimal= 0.2392 was considered the best choice, which results in the optimal frequency of 2.2 MHz at the radiusof 0.6 mm. To verify this optimal frequency, experiments under two working frequencies of 1.0282 MHz and 2.2579 MHz were conducted. Temperature rise curves in the chicken breast tissue showed good agreements between experiments and modeling results, which proved the effectiveness of the modeling. In addition, experiments showed an ablated area with a diameter of 1.03±0.12 mm under continuous excitation of 2.2579 MHz and 5 s. Conclusion:The developed DPLUS advanced the AW applicators towards thermal ablation applications.SignificanceThis study provides the evidence for recognizing AW applicators as a technique for thermal ablation.
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