Excessive gestational weight gain is associated with severe maternal morbidity.
Excessive gestational weight gain is associated with severe maternal morbidity.
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DOI：
10.1016/j.annepidem.2020.06.009
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发表时间：
2020-10
影响因子：
5.6
通讯作者：
Bodnar LM
中科院分区：
文献类型：
--
作者：
Freese KE;Himes KP;Hutcheon JA;Parisi SM;Brooks MM;McTigue K;Bodnar LM
我们确定了妊娠期体重增加和严重的孕产妇发病率之间的关系。我们使用了宾夕法尼亚州匹兹堡Magee-Womens医院（2003-2012）84，241例分娩住院的数据。将总妊娠体重增加（kg）转换为胎龄标准化z评分。我们将重度孕产妇发病率定义为具有21个疾病控制中心诊断或程序代码中的≥1个，用于重度孕产妇发病率识别、重症监护室入院或延长产后住院时间。我们使用多变量逻辑回归分析来确定调整混杂因素后体重增加和严重孕产妇发病率之间的关系。妊娠期增重z评分高与严重孕产妇发病风险增加相关。与z评分0 SD相比（相当于正常体重女性在40周时体重为16 kg），风险差异z评分−2 SD（7 kg）、−1 SD（11 kg）+1 SD（23 kg）和+2 SD（31 kg）的95%置信区间为1.5（-0.71，3.7）、0.056（-0.81，0.93）、3.4（1.7，5.0）和8.6（4.0，13）/1000次分娩。结果没有因分娩时的胎龄或孕前体重指数而变化。随着妊娠体重增加，严重孕产妇发病率的风险增加，这可能使科学家能够了解和预防这种严重的情况。
We determined the association between gestational weight gain and severe maternal morbidity. We used data on 84,241 delivery hospitalizations at Magee-Womens Hospital, Pittsburgh, Pennsylvania (2003–2012). Total gestational weight gain (kg) was converted to gestational age-standardized z-scores. We defined severe maternal morbidity as having ≥1 of the 21 Centers for Disease Control diagnosis or procedure codes for severe maternal morbidity identification, intensive care unit admission, or extended postpartum stay. We used multivariable logistic regression to determine the association between weight gain and severe maternal morbidity after confounder adjustment. High gestational weight gain z-scores were associated with an increased risk of severe maternal morbidity. Compared with z-score 0 SD (equivalent to 16 kg at 40 weeks in a normal weight woman), risk differences (95% confidence intervals) for z-scores −2 SD (7 kg), −1 SD (11 kg) +1 SD (23 kg), and +2 SD (31 kg) were 1.5 (−0.71, 3.7), 0.056 (−0.81, 0.93), 3.4 (1.7, 5.0), and 8.6 (4.0, 13) per 1000 deliveries. Results did not vary by gestational age at delivery or prepregnancy body mass index. The increased risk of severe maternal morbidity with high pregnancy weight gain may allow scientists to understand and prevent this serious condition.
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DOI：
10.1136/bmj.b2393
发表时间：
2009-06-29
期刊：
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影响因子：
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影响因子：
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