Single-walled carbon nanotubes as a multimodal-thermoacoustic and photoacoustic-contrast agent.

Single-walled carbon nanotubes as a multimodal-thermoacoustic and photoacoustic-contrast agent.
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DOI:
10.1117/1.3147407
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发表时间:
2009-05
影响因子:
3.5
通讯作者:
Wang LV
Wang LV
中科院分区:
医学3区
文献类型:
--
作者:
Pramanik M;Swierczewska M;Green D;Sitharaman B;Wang LV

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我们已经开发了一种新的基于碳纳米管的造影剂的热声和光声断层扫描。与去离子水相比,单壁碳纳米管在3 GHz的热声层析成像中表现出超过两倍的信号增强。与血液相比,它们在1064 nm波长下的光声层析成像显示出超过6倍的信号增强。组织模型成像研究进一步证实了单壁碳纳米管的大对比度增强。
We have developed a novel carbon nanotube-based contrast agent for both thermoacoustic and photoacoustic tomography. In comparison with de-ionized water, single-walled carbon nanotubes exhibited more than two-fold signal enhancement for thermoacoustic tomography at 3 GHz. In comparison with blood, they exhibited more than six-fold signal enhancement for photoacoustic tomography at 1064 nm wavelength. The large contrast enhancement of single-walled carbon nanotubes was further corroborated by tissue phantom imaging studies.
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