N-acyl homoserine lactone-producing Pseudomonas putida strain T2-2 from human tongue surface.
N-acyl homoserine lactone-producing Pseudomonas putida strain T2-2 from human tongue surface.
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DOI：
10.3390/s131013192
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发表时间：
2013-09-30
期刊：
影响因子：
--
通讯作者：
Chan KG
中科院分区：
文献类型：
--
作者：
Chen JW;Chin S;Tee KK;Yin WF;Choo YM;Chan KG
细菌细胞间通讯（群体感应）是指细菌基因表达对微生物种群密度变化的反应。群体感应细菌产生，释放和响应化学信号分子称为自诱导物。细菌使用两种类型的自诱导物，即自诱导物-1（AI-1）和自诱导物-2（AI-2），其中前者是N-酰基高丝氨酸内酯，后者是luxS基因的产物。大多数文献表明，大多数口腔细菌使用AI-2进行群体感应，但很少使用AI-1系统。本文报道从口腔中分离到一株恶臭假单胞菌T2-2。利用高分辨质谱，表明该分离物产生N-辛酰基高丝氨酸内酯（C8-HSL）和N-十二酰基高丝氨酸内酯（C12-HSL）分子。本文首次报道了从人舌表面分离的恶臭假单胞菌T2-2株具有群体感应功能，并鉴定了其群体感应分子。
Bacterial cell-to-cell communication (quorum sensing) refers to the regulation of bacterial gene expression in response to changes in microbial population density. Quorum sensing bacteria produce, release and respond to chemical signal molecules called autoinducers. Bacteria use two types of autoinducers, namely autoinducer-1 (AI-1) and autoinducer-2 (AI-2) where the former are N-acylhomoserine lactones and the latter is a product of the luxS gene. Most of the reported literatures show that the majority of oral bacteria use AI-2 for quorum sensing but rarely the AI-1 system. Here we report the isolation of Pseudomonas putida strain T2-2 from the oral cavity. Using high resolution mass spectrometry, it is shown that this isolate produced N-octanoylhomoserine lactone (C8-HSL) and N-dodecanoylhomoserine lactone (C12-HSL) molecules. This is the first report of the finding of quorum sensing of P. putida strain T2-2 isolated from the human tongue surface and their quorum sensing molecules were identified.
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影响因子：
3.2
作者：
Balestrino, D;Haagensen, JAJ;Forestier, C
通讯作者：
Forestier, C
影响因子：
4.4
作者：
Gan HM;Hudson AO;Rahman AY;Chan KG;Savka MA
通讯作者：
Savka MA
影响因子：
4.2
作者：
Chan KG;Atkinson S;Mathee K;Sam CK;Chhabra SR;Cámara M;Koh CL;Williams P
通讯作者：
Williams P
DOI：
10.1007/s10482-010-9438-0
发表时间：
2010-10-01
影响因子：
2.6
作者：
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通讯作者：
Koh, Chong-Lek
影响因子：
3.2
作者：
Barrios, AFG;Zuo, RJ;Wood, TK
通讯作者：
Wood, TK