New approaches and procedures for cancer treatment: Current perspectives.
New approaches and procedures for cancer treatment: Current perspectives.
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DOI：
10.1177/20503121211034366
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发表时间：
2021
影响因子：
2.3
通讯作者：
Manyazewal T
中科院分区：
文献类型：
--
作者：
Debela DT;Muzazu SG;Heraro KD;Ndalama MT;Mesele BW;Haile DC;Kitui SK;Manyazewal T
癌症是一个全球性的健康问题，导致全球六分之一的死亡。治疗癌症是一个非常复杂的过程。传统的治疗方法，如手术、化疗和放疗，一直在使用，而近年来也取得了重大进展，包括干细胞治疗、靶向治疗、消融治疗、纳米颗粒、天然抗氧化剂、放射学、化学动力学治疗、声动力学治疗和基于铁中毒的治疗。目前肿瘤学研究的重点是开发安全有效的肿瘤纳米药物。干细胞疗法通过靶向原发和转移性癌症病灶，在再生和修复病变或受损组织方面带来了令人鼓舞的疗效，纳米颗粒带来了新的诊断和治疗选择。靶向治疗具有突破性的潜力，可以抑制特定癌细胞的生长和扩散，对健康细胞的损害较小。消融治疗已经成为一种无需开腹手术即可烧伤或冻结癌症的微创治疗方法。天然抗氧化剂显示出追踪自由基和中和其有害影响的潜力，从而治疗或预防癌症。一些新技术目前正在临床试验中进行研究，其中一些已经获得批准。这篇综述介绍了癌症治疗的最新进展和突破。
Cancer is a global health problem responsible for one in six deaths worldwide. Treating cancer has been a highly complex process. Conventional treatment approaches, such as surgery, chemotherapy, and radiotherapy, have been in use, while significant advances are being made in recent times, including stem cell therapy, targeted therapy, ablation therapy, nanoparticles, natural antioxidants, radionics, chemodynamic therapy, sonodynamic therapy, and ferroptosis-based therapy. Current methods in oncology focus on the development of safe and efficient cancer nanomedicines. Stem cell therapy has brought promising efficacy in regenerating and repairing diseased or damaged tissues by targeting both primary and metastatic cancer foci, and nanoparticles brought new diagnostic and therapeutic options. Targeted therapy possessed breakthrough potential inhibiting the growth and spread of specific cancer cells, causing less damage to healthy cells. Ablation therapy has emerged as a minimally invasive procedure that burns or freezes cancers without the need for open surgery. Natural antioxidants demonstrated potential tracking down free radicals and neutralizing their harmful effects thereby treating or preventing cancer. Several new technologies are currently under research in clinical trials, and some of them have already been approved. This review presented an update on recent advances and breakthroughs in cancer therapies.
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影响因子：
5.2
作者：
Arruebo M;Vilaboa N;Sáez-Gutierrez B;Lambea J;Tres A;Valladares M;González-Fernández A
通讯作者：
González-Fernández A
DOI：
10.1016/b978-0-12-397927-8.00004-x
发表时间：
2012
期刊：
Advances in pharmacology (San Diego, Calif.)
影响因子：
--
作者：
Bailey, Kate M;Wojtkowiak, Jonathan W;Hashim, Arig Ibrahim;Gillies, Robert J
通讯作者：
Gillies, Robert J
影响因子：
0.6
作者：
Brace C
通讯作者：
Brace C
影响因子：
5.2
作者：
Charmsaz, Sara;Collins, Denis M.;Prencipe, Maria
通讯作者：
Prencipe, Maria
影响因子：
82.9
作者：
Ganesh K;Massagué J
通讯作者：
Massagué J