Causes of sex ratio bias may account for unisexual sterility in hybrids: a new explanation of Haldane's rule and related phenomena.
Causes of sex ratio bias may account for unisexual sterility in hybrids: a new explanation of Haldane's rule and related phenomena.
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性别比例偏差的原因可能是杂种中单性不育的原因：霍尔丹规则和相关现象的新解释。
作者：
L. Hurst;A. Pomiankowski
单性杂种的破坏可以解释为在杂种杂交的物种中已经分化的性比扭曲者之间的相互作用。一类单性杂种的破坏是由Halfman法则描述的，即不存在的、不能存活的或不育的性别是异配子性别。这种影响主要是由于X和Y染色体之间的不相容性。我们认为，这种不相容性是由于减数分裂驱动基因之间的相互不平衡，这更有可能在性染色体上比常染色体上进化。具有性染色体驱动的分类群的发生率与适用Halfman规则的分类群密切匹配：鸟类、哺乳动物、鳞翅目和双翅目。我们预测，Halfman的规则是不普遍的，但是正确的类群与性染色体减数分裂驱动。第二类杂交破坏影响物种的雄性，而不管哪种性别是异配子。通常，负责这种破坏形式的基因是细胞质的。这些情况是占细胞质性比扭曲抑制释放时，在一个新的核细胞型。由于细胞质的完全母体传递，细胞质性比扭曲只导致雌性偏向的性比。这种不对称性解释了为什么杂交破坏仅限于雄性。
Unisexual hybrid disruption can be accounted for by interactions between sex ratio distorters which have diverged in the species of the hybrid cross. One class of unisexual hybrid disruption is described by Haldane's rule, namely that the sex which is absent, inviable or sterile is the heterogametic sex. This effect is mainly due to incompatibility between X and Y chromosomes. We propose that this incompatibility is due to a mutual imbalance between meiotic drive genes, which are more likely to evolve on sex chromosomes than autosomes. The incidences of taxa with sex chromosome drive closely matches those where Haldane's rule applies: Aves, Mammalia, Lepidoptera and Diptera. We predict that Haldane's rule is not universal but is correct for taxa with sex chromosome meiotic drive. A second class of hybrid disruption affects the male of the species regardless of which sex is heterogametic. Typically the genes responsible for this form of disruption are cytoplasmic. These instances are accounted for by the release from suppression of cytoplasmic sex ratio distorters when in a novel nuclear cytotype. Due to the exclusively maternal transmission of cytoplasm, cytoplasmic sex ratio distorters cause only female-biased sex ratios. This asymmetry explains why hybrid disruption is limited to the male.
假暗果蝇和小果蝇杂交种雄性和雌性不育的遗传学。
影响因子：
3.3
作者：
Orr,HA
通讯作者：
Orr,HA
果蝇 X 染色体系选择的组成部分：通过减数分裂驱动和活力选择改变性别比例。
影响因子：
3.3
作者：
Curtsinger,JW
通讯作者：
Curtsinger,JW