The Validity of Ultrasound Technology in Providing an Indirect Estimate of Muscle Glycogen Concentrations Is Equivocal.
The Validity of Ultrasound Technology in Providing an Indirect Estimate of Muscle Glycogen Concentrations Is Equivocal.
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DOI：
10.3390/nu13072371
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发表时间：
2021-07-11
期刊：
影响因子：
5.9
通讯作者：
Burke LM
中科院分区：
文献类型：
--
作者：
Bone JL;Ross ML;Tomcik KA;Jeacocke NA;McKay AKA;Burke LM
运动营养学的研究人员和从业人员将从一种快速、便携、无创的技术中受益匪浅，这种技术可以在实验室和现场测量肌糖原。这解释了对MuscleSound®的兴趣，这是第一个商业系统，使用高频超声技术和基于云的专利软件的图像分析，从超声图像的回声性估计肌糖原含量。这项技术主要基于肌肉含水量，它被认为是糖原的代用物。尽管早期验证研究有希望，但来自独立小组的较新的研究报告了不同的结果，MuscleSound®评分未能与活检获得的混合肌肉样本的糖原含量相关，也未能显示与各种饮食和运动策略相关的肌糖原的预期变化。与评估部位有关的问题的解释并不能解释这些差异，并且在肌肉中糖原与水的比例恒定的前提下存在实质性问题。虽然进一步研究这项技术是有必要的，但目前的证据表明，MuscleSound®技术可以提供有关肌糖原储存的有效和可操作的信息，充其量是模棱两可的。
Researchers and practitioners in sports nutrition would greatly benefit from a rapid, portable, and non-invasive technique to measure muscle glycogen, both in the laboratory and field. This explains the interest in MuscleSound®, the first commercial system to use high-frequency ultrasound technology and image analysis from patented cloud-based software to estimate muscle glycogen content from the echogenicity of the ultrasound image. This technique is based largely on muscle water content, which is presumed to act as a proxy for glycogen. Despite the promise of early validation studies, newer studies from independent groups reported discrepant results, with MuscleSound® scores failing to correlate with the glycogen content of biopsy-derived mixed muscle samples or to show the expected changes in muscle glycogen associated with various diet and exercise strategies. The explanation of issues related to the site of assessment do not account for these discrepancies, and there are substantial problems with the premise that the ratio of glycogen to water in the muscle is constant. Although further studies investigating this technique are warranted, current evidence that MuscleSound® technology can provide valid and actionable information around muscle glycogen stores is at best equivocal.
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影响因子：
2.5
作者：
Impey SG;Hammond KM;Shepherd SO;Sharples AP;Stewart C;Limb M;Smith K;Philp A;Jeromson S;Hamilton DL;Close GL;Morton JP
通讯作者：
Morton JP
影响因子：
2.5
作者：
Deminice, R.;Rosa, F. T.;Freitas, E.
通讯作者：
Freitas, E.
影响因子：
5.9
作者：
Hearris MA;Hammond KM;Fell JM;Morton JP
通讯作者：
Morton JP
DOI：
10.1111/j.1748-1716.1967.tb03719.x
发表时间：
1967-01-01
期刊：
ACTA PHYSIOLOGICA SCANDINAVICA
影响因子：
--
作者：
HERMANSEN, L;HULTMAN, E;SALTIN, B
通讯作者：
SALTIN, B
DOI：
10.1249/mss.0000000000001174
发表时间：
2017-05-01
期刊：
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
影响因子：
--
作者：
Bone, Julia L.;Ross, Megan L.;Burke, Louise M.
通讯作者：
Burke, Louise M.